2. Anti-infection
  3. Antibiotic
  4. Sapurimycin

Sapurimycin is an antitumor antibiotic isolated from Streptomyces DO-116 and belongs to the capramycin family. Sapurimycin exhibits potent activity against Gram-positive bacteria and exhibits significant antitumor effects against leukemia P388 and sarcoma 180 in mouse models. In vitro studies have shown that Sapurimycin can induce single-strand breaks in supercoiled plasmid DNA.

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Sapurimycin Chemical Structure

Sapurimycin Chemical Structure

CAS No. : 132609-35-9

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Sapurimycin Related Antibodies

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Description

Sapurimycin is an antitumor antibiotic isolated from Streptomyces DO-116 and belongs to the capramycin family. Sapurimycin exhibits potent activity against Gram-positive bacteria and exhibits significant antitumor effects against leukemia P388 and sarcoma 180 in mouse models. In vitro studies have shown that Sapurimycin can induce single-strand breaks in supercoiled plasmid DNA[1].

Molecular Weight

462.41

Formula

C25H18O9
CAS No.
SMILES

O=C(O)CC(C=C1C(C2=C3C(O)=CC=C2O)=O)=C(C(C=C([C@@]4(C)O[C@H]4/C=C\C)O5)=O)C5=C1C3=O
Structure Classification
Initial Source

Streptomyces
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Sapurimycin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sapurimycin132609-35-9Antibiotic DC 116Antibiotic DC116Antibiotic DC-116AntibioticInhibitorinhibitorinhibit

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