2. Others
  3. Isotope-Labeled Compounds
  4. Saroglitazar-d4

Saroglitazar-d4 is the deuterium-labeled Saroglitazar (HY-19937). Saroglitazar-d4 is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.

For research use only. We do not sell to patients.

Saroglitazar-d<sub>4</sub> Chemical Structure

Saroglitazar-d4 Chemical Structure

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Other Forms of Saroglitazar-d4:

Saroglitazar-d4 Related Antibodies

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Description

Saroglitazar-d4 is the deuterium-labeled Saroglitazar (HY-19937). Saroglitazar-d4 is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Saroglitazar-d4 Related Antibodies
Molecular Weight

443.59

Formula

C25H25D4NO4S
Unlabeled CAS

495399-09-2
SMILES

OC([C@@H](OCC)CC1=CC=C(OC([2H])([2H])C([2H])([2H])N2C(C)=CC=C2C3=CC=C(SC)C=C3)C=C1)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Saroglitazar-d4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Saroglitazar-d4Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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HY-19937S1
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