1. Anti-infection
  2. SARS-CoV
  3. SARS-CoV-2-IN-20

SARS-CoV-2-IN-20 (Compound 1a) is a potent inhibitor of SARS-CoV-2 with an EC50 of 6.5 μM. SARS-CoV-2-IN-20 has the potential for the research of infection diseases.

For research use only. We do not sell to patients.

SARS-CoV-2-IN-20 Chemical Structure

SARS-CoV-2-IN-20 Chemical Structure

CAS No. : 1260244-33-4

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Description

SARS-CoV-2-IN-20 (Compound 1a) is a potent inhibitor of SARS-CoV-2 with an EC50 of 6.5 μM. SARS-CoV-2-IN-20 has the potential for the research of infection diseases[1].

Cellular Effect
Cell Line Type Value Description References
HepG2 CC50
21.58 μg/mL
Compound: 1
Cytotoxicity against human HepG2 cells assessed as reduction in cell number after 24 hrs by bioluminescence assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell number after 24 hrs by bioluminescence assay
[PMID: 29908437]
HepG2 CC50
21.6 μg/mL
Compound: 1
Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs by ATP bioluminescence assay
Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 24 hrs by ATP bioluminescence assay
[PMID: 30067360]
Vero C1008 CC50
21.2 μM
Compound: 1a
Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay
Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay
[PMID: 35571875]
Molecular Weight

378.51

Formula

C24H30N2O2

CAS No.
SMILES

CCCOC1=CC=C(C=C1)C2=NC3=CC=CC=C3C(OCCN(CC)CC)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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SARS-CoV-2-IN-20 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SARS-CoV-2-IN-20
Cat. No.:
HY-146381
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