2. Anti-infection
  3. SARS-CoV
  4. SARS-CoV-2 Mpro-IN-14

SARS-CoV-2 Mpro-IN-14 (Compound 19) is an inhibitor of SARS-CoV-2 Mpro with an IC50 of 0.044 μM. SARS-CoV-2 Mpro-IN-14 exhibits water solubility, has no cytotoxicity, and can be used in the study of COVID-19.

For research use only. We do not sell to patients.

SARS-CoV-2 Mpro-IN-14 Chemical Structure

SARS-CoV-2 Mpro-IN-14 Chemical Structure

CAS No. : 2679814-93-6

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SARS-CoV-2 Mpro-IN-14 Related Antibodies

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Description

SARS-CoV-2 Mpro-IN-14 (Compound 19) is an inhibitor of SARS-CoV-2 Mpro with an IC50 of 0.044 μM. SARS-CoV-2 Mpro-IN-14 exhibits water solubility, has no cytotoxicity, and can be used in the study of COVID-19[1].

IC50 & Target

IC50: 0.044 μM (SARS-CoV-2 Mpro)[1]
Cellular Effect
Cell Line Type Value Description References
16HBE14o- CC50
> 32.5 μM
Compound: 19
Cytotoxicity against human 16HBE14o- after 72 hrs by MTT assay
Cytotoxicity against human 16HBE14o- after 72 hrs by MTT assay
[PMID: 34408808]
Vero C1008 CC50
> 32.5 μM
Compound: 19
Cytotoxicity against African green monkey Vero E6 cells after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero E6 cells after 72 hrs by MTT assay
[PMID: 34408808]
Molecular Weight

565.38

Formula

C28H19Cl2FN4O4
CAS No.
SMILES

O=C1NC(N(C)C=C1C(C=C2C3=CC(OCC4=C(Cl)C=CC=C4)=C(F)C(Cl)=C3)=CN(C5=CC=CN=C5)C2=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SARS-CoV-2 Mpro-IN-14 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARS-CoV-2 Mpro-IN-142679814-93-6SARS-CoVSARS coronavirusCOVID-19SARS-CoV-2Inhibitorinhibitorinhibit

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