1. Anti-infection
  2. SARS-CoV Virus Protease
  3. SARS-CoV-2 Mpro-IN-23

SARS-CoV-2 Mpro-IN-23 (Compound 2) is an inhibitor for SARS-CoV-2 main protease (Mpro), which inhibits wildtype Mpro and mutant Mpro variants, with IC50 of 0.057-0.92 μM. SARS-CoV-2 Mpro-IN-23 inhibits the post-entry viral processes of wild-type SARS-CoV-2 single-round infectious particles (SRIPs), suppresses the viral replication of Mpro wildtype and Mpro mutants with EC50 of 0.02-0.52 μM.

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SARS-CoV-2 Mpro-IN-23 Chemical Structure

SARS-CoV-2 Mpro-IN-23 Chemical Structure

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Description

SARS-CoV-2 Mpro-IN-23 (Compound 2) is an inhibitor for SARS-CoV-2 main protease (Mpro), which inhibits wildtype Mpro and mutant Mpro variants, with IC50 of 0.057-0.92 μM. SARS-CoV-2 Mpro-IN-23 inhibits the post-entry viral processes of wild-type SARS-CoV-2 single-round infectious particles (SRIPs), suppresses the viral replication of Mpro wildtype and Mpro mutants with EC50 of 0.02-0.52 μM[1].

Molecular Weight

1145.38

Formula

C54H84N2O20S2

SMILES

C[C@@]1(CC[C@]2([C@@]([H])(C1)C([C@]3(CC2)C)=CC(C4[C@]3(CC[C@@]5([C@@]4(CC[C@@H](C5(C)C)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)C(ONC(C(OC)=O)CCSC)=O)O)O)C(ONC(CCSC)C(OC)=O)=O)C)[H])C)=O)C)C(O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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SARS-CoV-2 Mpro-IN-23 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SARS-CoV-2 Mpro-IN-23
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HY-161777
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