2. Anti-infection
  3. SARS-CoV
  4. SARS-CoV MPro-IN-1

SARS-CoV MPro-IN-1 is a SARS-CoV-2 3CLpro covalent inhibitor, with an IC50 of 40 nM. SARS-CoV MPro-IN-1 shows good anti-SARS-CoV-2-infection activity in cell culture with an EC50 of 0.33 μM. SARS-CoV MPro-IN-1 has the potential for COVID-19 research.

For research use only. We do not sell to patients.

SARS-CoV MPro-IN-1 Chemical Structure

SARS-CoV MPro-IN-1 Chemical Structure

CAS No. : 2413716-71-7

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Based on 1 publication(s) in Google Scholar

SARS-CoV MPro-IN-1 Related Antibodies

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Description

SARS-CoV MPro-IN-1 is a SARS-CoV-2 3CLpro covalent inhibitor, with an IC50 of 40 nM. SARS-CoV MPro-IN-1 shows good anti-SARS-CoV-2-infection activity in cell culture with an EC50 of 0.33 μM. SARS-CoV MPro-IN-1 has the potential for COVID-19 research[1].

In Vivo

SARS-CoV MPro-IN-1 (compound 11b) (5 mg/kg; intravenous drip administration) shows the t1/2 is <1.65 hours and the clearance rate is 20.6 mL/min/mg[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

464.49

Formula

C25H25FN4O4
CAS No.
SMILES

O=C(C1=CC2=CC=CC=C2N1)N[C@H](C(N[C@H](C=O)C[C@H](CCN3)C3=O)=O)CC4=CC(F)=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SARS-CoV MPro-IN-1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARS-CoV MPro-IN-12413716-71-7SARS-CoVSARS coronavirusInhibitorinhibitorinhibit

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