2. NF-κB
  3. NF-κB
  4. Sauchinone (Standard)

Sauchinone (Standard) is the analytical standard of Sauchinone. This product is intended for research and analytical applications. Sauchinone is a diastereomeric lignan isolated from Saururus chinensis (Saururaceae). Sauchinone inhibits LPS-inducible iNOS, TNF-α and COX-2 expression through suppression of I-κBα phosphorylation and p65 nuclear translocation. Sauchinone has anti-inflammatory and antioxidant activity.

For research use only. We do not sell to patients.

Sauchinone (Standard) Chemical Structure

Sauchinone (Standard) Chemical Structure

CAS No. : 177931-17-8

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Description
Molecular Weight

356.37

Formula

C20H20O6
CAS No.
SMILES

C[C@@H]([C@@H](C[C@]12[H])C)[C@](C(C=C(OCO3)C3=C4)=C4O5)([H])[C@@]1([H])[C@]5(OCO6)C6=CC2=O
Structure Classification
Initial Source
Storage

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Sauchinone (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sauchinone (Standard)177931-17-8NF-κBNuclear factor-κBNuclear factor-kappaBDiastereomericlignanLPSiNOSTNF-αCOX-2anti-inflammatoryantioxidantInhibitorinhibitorinhibit

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