2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. SB399885

SB399885 is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with pKi values 9.11 and 9.02 for human recombinant and native 5-HT6 receptors, respectively. SB399885 has cognitive enhancing properties.

For research use only. We do not sell to patients.

SB399885 Chemical Structure

SB399885 Chemical Structure

CAS No. : 402713-80-8

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SB399885 Related Antibodies

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Description

SB399885 is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with pKi values 9.11 and 9.02 for human recombinant and native 5-HT6 receptors, respectively. SB399885 has cognitive enhancing properties[1].

IC50 & Target[1]

5-HT6 Receptor

9.02 (pKi)

Human 5-HT6 Receptor

9.11 (pKi)

Molecular Weight

446.35

Formula

C18H21Cl2N3O4S
CAS No.
SMILES

COC1=C(N2CCNCC2)C=C(S(NC3=C(C(Cl)=CC(Cl)=C3)OC)(=O)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SB399885 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SB399885402713-80-8SB 399885SB-3998855-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptorselectivebrain penetrantorally activecognitive enhancing propertiesInhibitorinhibitorinhibit

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