SC 34301 (Synonyms: Enisoprost)

Cat. No.: HY-105052: FAQs
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SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice.

For research use only. We do not sell to patients.

SC 34301 Chemical Structure

CAS No. : 81026-63-3

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Description

SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice^[1]^[2].

In Vivo

SC 34301 (200 µg/kg; p.o.; once a day for three days) significantly reduces bacterial translocation and improves survival^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	BALB/c mice (E. coli, burned)^[1]
Dosage:	200 µg/kg
Administration:	P.o.; once a day for three days
Result:	Significantly reduced the degree of bacterial translocation as measured by blood dpm counts, improved survival rate to 60% in burned mice.

Molecular Weight

380.52

Formula

C₂₂H₃₆O₅

CAS No.

81026-63-3

SMILES

CCCCC(C)(O)C/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CC/C=C\CCC(OC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Pollak R, et al. A trial of the prostaglandin E1 analogue, enisoprost, to reverse chronic cyclosporine-associated renal dysfunction. Am J Kidney Dis. 1992 Oct;20(4):336-41. [Content Brief]

[2]. Fukushima R, et al. The degree of bacterial translocation is a determinant factor for mortality after burn injury and is improved by prostaglandin analogs. Ann Surg. 1992 Oct;216(4):438-44; discussion 444-5. [Content Brief]

SC 34301 Related Classifications

Endocrinology

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SC 3430181026-63-3EnisoprostSC34301SC-34301Prostaglandin ReceptorInhibitorinhibitorinhibit

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