2. GPCR/G Protein
  3. Adenosine Receptor
  4. SCH442416 (Standard)

SCH442416 (Standard) is the analytical standard of SCH442416. This product is intended for research and analytical applications. SCH442416 is a potent, selective and brain-penetrant antagonist of adenosine A2A receptor (A2AR), with Kis of 0.048 and 0.5 nM for human and rat A2AR respectively. SCH442416 displays more than 23000-fold selectivity over A1R, A2BR, and A3R (Ki=1111, 10000, and 10000 nM, respectively). SCH442416 can be used for imaging of adenosine A2A receptors in rat and primate brain[1][2].

For research use only. We do not sell to patients.

SCH442416 (Standard) Chemical Structure

SCH442416 (Standard) Chemical Structure

CAS No. : 316173-57-6

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SCH442416 (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SCH442416 (Standard)316173-57-6Adenosine ReceptorP1 receptoradenosineA2AimagingInhibitorinhibitorinhibit

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