SDH-IN-4 

SDH-IN-4 (compound B6) is a selective inhibitor against succinate dehydrogenase (SDH) with an IC₅₀ value of 0.28 μg/mL. SDH-IN-4 has highly efficient and broad-spectrum antifungal activity, against R. solani with an EC₅₀ value of 0.23 μg/mL^[1].

SDH-IN-4 (10 μg/mL, 3-5 days) inhibits mycelium growth of fungal R. solani, F. graminearum, B. cinerea and A. solani^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SDH-IN-4 (100 μg/mL, 5 days) inhibits R. solani in detached rice leaves was 87.48%^[1].
SDH-IN-4 (20 μg/mL, 0.5-3 h) inhibits the growth and development of mycelia of R. solani and causes serious damage to the mycelial cell membrane^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

389.18

C₁₁H₉Cl₂F₃N₄O₂S

2982993-88-2

O=S(C1=C(C)NN=C1C(F)(F)F)(NNC2=CC=C(Cl)C=C2Cl)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Chai JQ, et al. Potential Succinate Dehydrogenase Inhibitors Bearing a Novel Pyrazole-4-sulfonohydrazide Scaffold: Molecular Design, Antifungal Evaluation, and Action Mechanism. J Agric Food Chem. 2023 Jun 21;71(24):9266-9279.  [Content Brief]