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Hcst

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  • HY-P75310

    Hematopoietic cell signal transducer; Hcst; DAP10; KAP10; PIK3AP

    Human HEK293
    DAP10 is a transmembrane adapter protein that forms the activating receptor KLRK1-HCST, which is critical for cytotoxicity in target cells expressing stress-inducing ligands. It is activated by ULBP, triggering calcium mobilization and activating PI3K, MAP2K/ERK and JAK2/STAT5 signaling pathways. DAP10 Protein, Human (HEK293, mFc) is the recombinant human-derived DAP10 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of DAP10 Protein, Human (HEK293, mFc) is 30 a.a., with molecular weight of ~33-45 kDa.

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