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Sema5a

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  • HY-P70496
    Semaphorin-5A/SEMA5A Protein, Human (HEK293, His)

    Semaphorin-5a; Semaphorin-F; Sema F; Sema5a; SemaF

    		 Human HEK293
    Semaphorin-5A/SEMA5A proteins act as bifunctional axon guidance signals, exerting attraction via heparan sulfate proteoglycans and inhibitory effects via chondroitin sulfate proteoglycans. As a ligand for the PLXNB3 receptor, SEMA5A disrupts glioma cell migration and invasion and induces cell collapse. Semaphorin-5A/SEMA5A Protein, Human (HEK293, His) is the recombinant human-derived Semaphorin-5A/SEMA5A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Semaphorin-5A/SEMA5A Protein, Human (HEK293, His) is 743 a.a., with molecular weight of ~100.0 kDa.
  • HY-P74560
    Semaphorin-5A/SEMA5A Protein, Human (HEK293, Fc)

    Semaphorin-5a; Semaphorin-F; Sema F; Sema5a; SemaF

    		 Human HEK293
    Semaphorin-5A/SEMA5A Protein acts as a bifunctional axonal guidance cue, with attractive effects via heparan sulfate proteoglycans and inhibitory effects through chondroitin sulfate proteoglycans. As a ligand for PLXNB3 receptor, SEMA5A disrupts glioma cell migration and invasion, inducing cellular collapse. It may also promote angiogenesis by affecting endothelial cell proliferation and migration, while inhibiting apoptosis. SEMA5A's binding to PLXNB3 reveals its diverse roles in axon guidance, cell migration, and angiogenesis in both normal and pathological conditions. Semaphorin-5A/SEMA5A Protein, Human (HEK293, Fc) is the recombinant human-derived Semaphorin-5A/SEMA5A protein, expressed by HEK293, with C-hFc labeled tag. The total length of Semaphorin-5A/SEMA5A Protein, Human (HEK293, Fc) is 765 a.a., with molecular weight of 125-135 kDa.

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