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ALK

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  • HY-P72454
    TGFBR1/ALK-5 Protein, Mouse (HEK293, Fc)

    TGF-beta receptor type-1; ALK-5; SKR4; TbetaR-I; AAT5

    		 Mouse HEK293
    TGFBR1 is a transmembrane kinase that cooperates with TGFBR2 to form the TGF-β receptor complex.This complex is activated by cytokines and regulates a variety of processes, including cell cycle arrest, mesenchymal cell control, wound healing, and carcinogenesis.TGFBR1/ALK-5 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived TGFBR1/ALK-5 protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P7481
    ACVRL1/ALK1 Protein, Mouse (HEK293, Fc)

    rMuActivin Receptor-like Kinase 1, C-Fc; ALK-1; ACVRL1; Activin Receptor-like Kinase 1

    		 Mouse HEK293
    ALK-1, also known as ACVRL1, is a type I receptor for TGF-β superfamily with 2 ligands, BMP9 and BMP10. ALK-1 is predominantly expressed in endothelial cells and plays a critical role in regulating developmental and pathological angiogenesis. ACVRL1/ALK1 Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 97 amino acids (D23-P119).
  • HY-P7483
    BMPR1A/ALK-3 Protein, Mouse (129a.a, HEK293, His-Fc)

    Bone morphogenetic protein receptor type-1A; ALK-3; SKR5; CD292; ACVRLK3; BMPR-IA

    		 Mouse HEK293
    BMPR1A/ALK-3 protein (ACVRLK3) is the receptor bone morphogenetic protein (BMP) type I receptors, widely expressed in tissues. BMPR1A/ALK-3 protein mediates iron metabolism factor hepcidin expression, interacts with GDF5/6 to regulate chondrocyte differentiation and adipogenesis. BMPR1A-ID2/ZEB1-TGFBR2 signaling axis could serve as a potentia target for pulmonary arterial hypertension (PAH) and other endothelial-mesenchymal transition (EndoMT)-related vascular disorders. Mouse BMPR1A/ALK-3 has a full length of 532 a.a., with a motif (107-109 a.a.) mediating specificity for BMP ligand. BMPR1A/ALK-3 Protein, Mouse (129a.a, HEK293, His-Fc) is produced in HEK293 cells and has 129 amino acids (Q24-R152), with C-terminal Fc- and His-tags.
  • HY-P76902
    ENPP-7 Protein, Mouse (HEK293, His)

    Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; NPP-7; ALK-Smase

    		 Mouse HEK293
    The ENPP-7 protein acts as a choline-specific phosphodiesterase and is essential for sphingomyelin digestion, ceramide formation, and FA absorption in the gastrointestinal tract. It hydrolyzes sphingomyelin to release ceramide and phosphocholine. ENPP-7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ENPP-7 protein, expressed by HEK293 , with C-His labeled tag. The total length of ENPP-7 Protein, Mouse (HEK293, His) is 400 a.a., with molecular weight of ~60 kDa.
  • HY-P78041
    SLPI Protein, Mouse (HEK293, Fc)

    ALP; BLPI; HUSI-1; MPI; WAP4; WFDC4; ALK1; HUSI; SLPI

    		 Mouse HEK293
    The SLPI protein is an acid-stable protease inhibitor that modulates immune responses to bacterial infections.It downregulates responses to bacterial lipopolysaccharide (LPS) and modulates NF-kappa-B activation and inflammatory responses.SLPI Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived SLPI protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P76176
    BMPRIB/ALK-6 Protein, Mouse (HEK293, Fc)

    Bone morphogenetic protein receptor type-1B; BMPR-1B; CDw293

    		 Mouse HEK293
    BMPR1B/ALK-6 protein is a type I member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. BMPR1B/ALK-6 is the receptor for BMP-7/OP-1 and GDF-5, positively regulates chondrocyte differentiation through GDF-5 interaction. BMPR1B/ALK-6 also involves in SCUBE3/BMP-2/BMP-4 signals regulation, controlling growth, morphogenesis, and bone and teeth development. ALK-6/GDF-9/BMP-15 signals is essential in prolificacy of goat. The mouse BMPR1B/ALK-6 protein contains 502 amino acids and a transmembrane domain (127-148 a.a.). BMPRIB/ALK-6 Protein, Mouse (HEK293, Fc) is produced by HEK293 cells (K14-K126) with C-terminal hFc-tag.
  • HY-P7486
    Activin RIB/ALK-4 Protein, Mouse (HEK293, Fc)

    rMuActivin Receptor IB, C-Fc; ALK-4; Activin RIB; ACVR1B

    		 Mouse HEK293
    Activin RIB, also known as activin receptor type-1B (ACVR1B) or ALK-4, is a type I transmembrane serine/threonine kinase receptor that is part of the TGF-β receptor superfamily. Activin binds to a type II activin receptor (ACVR2or ACVR2B) and then recruits ACVR1B. Activin RIB/ALK-4 Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 95 amino acids (L32-E126).
  • HY-P72819
    ACVRL1/ALK1 Protein, Mouse (HEK293, His-Fc)

    Serine/threonine-protein kinase receptor R3; SKR3; ALK-1; TSR-I; ACVRL1

    		 Mouse HEK293
    ALK-1, also known as ACVRL1, is a type I receptor for TGF-β superfamily with 2 ligands, BMP9 and BMP10. ALK-1 is predominantly expressed in endothelial cells and plays a critical role in regulating developmental and pathological angiogenesis. ACVRL1/ALK1 Protein, Mouse (HEK293, His-Fc) is produced in HEK293 cells with a C-Terminal His-tag and a C-Terminal Fc-tag. It consists of 119 amino acids (M1-P119).

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