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Results for "

(-)-Pimobendan

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0204
    Pimobendan
    2 Publications Verification

    UD-CG115

    		 Phosphodiesterase (PDE) Cardiovascular Disease
    Pimobendan (UD-CG115) is a selective inhibitor of PDE3 with IC50 of 0.32 μM.
    Pimobendan
  • HY-B0204B
    (-)-Pimobendan

    (-)-UD-CG115

    		 Others Cardiovascular Disease
    (-)-Pimobedan is an isomer of pimobedan. It has the property of stereoselective partitioning or distribution into erythrocytes. The clearance of (-)-pimobedan from erythrocytes is significantly lower than that of (+)-pimobedan, which is entirely due to its stereoselective distribution into erythrocytes. This stereoselective property of (-)-pimobedan may explain the phenomenon previously reported that it produces a 1.5-fold greater contractile force than the (+)-isomer in detergent-treated myocardial specimens of guinea pigs and dogs. These properties suggest that (-)-pimobedan may have unique advantages in terms of in vivo distribution and pharmacological action, which may have important implications for its clinical use.
    (-)-Pimobendan
  • HY-B0204R
    Pimobendan (Standard)

    		Phosphodiesterase (PDE) Cardiovascular Disease
    Pimobendan (Standard) is the analytical standard of Pimobendan. This product is intended for research and analytical applications. Pimobendan (UD-CG115) is a selective inhibitor of PDE3 with IC50 of 0.32 μM.
    Pimobendan (Standard)
  • HY-B0204A
    Pimobendan hydrochloride

    UD-CG115 hydrochloride

    		 Phosphodiesterase (PDE) Cardiovascular Disease
    Pimobendan hydrochloride (UD-CG115 hydrochloride) is a selective inhibitor of PDE3 with IC50 of 0.32 μM.
    Pimobendan hydrochloride

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