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(-)-Trans-(1S,2S)-U-50488

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15997
    (-)-U-50488 hydrochloride

    (-)-Trans-(1S,2S)-U-50488 hydrochloride

    		 Opioid Receptor Infection Cancer
    (-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) is a selective kappa-opioid receptor (KOR) agonist (b>Kd=2.2 nM) over μ-opioid receptor (MOR) (b>Kd=430 nM). (-)-U-50488 hydrochloride is a more active enantiomer than (+)?trans-(1R,2R) U-50488 (HY-15997A)?or the (±)?trans-racemic mixture U-50488 (HY-15997B). (-)-U-50488 hydrochloride has a potent and sustained anti-HIV effect in fected blood monocyte-derived macrophages (MDM) .
    (-)-U-50488 hydrochloride
  • HY-130696
    (+)-U-50488

    (+)-Trans-(1R,2R)-U-50488

    		 Opioid Receptor Neurological Disease
    (+)-U-50488 ((+)-Trans-(1R,2R)-U-50488) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-)-Trans-(1S,2S)-U-50488 (HY-15997) .
    (+)-U-50488
  • HY-15997A
    (+)-U-50488 hydrochloride

    (+)-Trans-(1R,2R)-U-50488 hydrochloride

    		 Opioid Receptor Neurological Disease
    (+)-U-50488 (hydrochloride) (+)-Trans-(1R,2R)-U-50488 hydrochloride) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-)-Trans-(1S,2S)-U-50488 (HY-15997) .
    (+)-U-50488 hydrochloride

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