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Suberoylanilide hydroxamic acid-d5

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-115412
    Vorinostat-d5

    SAHA-d5; Suberoylanilide hydroxamic acid-d5

    		 HDAC Autophagy Mitophagy Filovirus Apoptosis HPV Infection Cancer
    Vorinostat-d5 (SAHA-d5) is the deuterium labeled Vorinostat. Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis . Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification .
    Vorinostat-d5

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