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Results for "

V-073

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Enterovirus (1) Isotope-Labeled Compounds (1) Virus Protease (1)
By Research Areas:	Infection (3)
Click Chemistry:	Alkynes (1)

4

Inhibitors & Agonists

1

Isotope-Labeled Compounds

1

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Pocapavir 3 Publications Verification SCH-48973; V-073	Enterovirus	Infection
Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections .

AG-7404	Virus Protease	Infection
AG-7404 is an inhibitor of picornaviral 3C protease, with anti-poliovirus activity (EC₅₀=0.080-0.674 μM). AG-7404 has synergy with V-073 (HY-104074) or BTA798 (HY-106254), and fully inhibits all V-073-resistant variants . AG-7404 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

H1PVAT	Others	Infection
H1PVAT is a potent and selective inhibitor of poliovirus serotypes (PV-1, PV-2, PV-3), and inhibits early stage of the replication. H1PVAT interacts with viral capsid directly and protects PV against heat inactivation .

Pocapavir-d3 SCH-48973-d₃; V-073-d₃	Isotope-Labeled Compounds	Others
Pocapavir-d₃ (SCH-48973-d₃; V-073-d₃)is the deuterium labeledPocapavir(HY-104074) . Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections .

Cat. No.	Product Name	Chemical Structure

Pocapavir-d3
Pocapavir-d₃ (SCH-48973-d₃; V-073-d₃)is the deuterium labeledPocapavir(HY-104074) . Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections .

Cat. No.	Product Name		Classification

AG-7404		Alkynes
AG-7404 is an inhibitor of picornaviral 3C protease, with anti-poliovirus activity (EC₅₀=0.080-0.674 μM). AG-7404 has synergy with V-073 (HY-104074) or BTA798 (HY-106254), and fully inhibits all V-073-resistant variants . AG-7404 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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