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21-Desoxycortisone

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W741510
    21-Deoxy Cortisone

    21-Desoxycortisone; NSC 38722

    		 Endogenous Metabolite Cardiovascular Disease
    21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is formed from 11-ketoprogesterone by the cytochrome P450 (CYP) isozyme CYP17A1, but can also be produced by oxidation of 21-deoxycortisone (HY-113405) by 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2). Congenital adrenal hyperplasia is an inborn error of metabolism characterized by a deficiency of 21-hydroxylase, and 21-Deoxy Cortisone levels are elevated in patients with congenital adrenal hyperplasia.
    21-Deoxy Cortisone

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