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3-Indoleacrylic acid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Endogenous Metabolite (1) Ferroptosis (1) Isotope-Labeled Compounds (1) Proton Pump (1) Reactive Oxygen Species (2)
By Research Areas:	Cancer (1) Metabolic Disease (1)

4

Inhibitors & Agonists

1

Natural
Products

1

Isotope-Labeled Compounds

Targets Recommended: Amino acid Transporter Amino Acid Derivatives Hydroxycarboxylic Acid Receptor (HCAR) Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

3-Indoleacrylic acid	Reactive Oxygen Species	Others
3-Indoleacrylic acid is a high-efficient antialgal agent. 3-Indoleacrylic acid increases reactive oxygen species (ROS) production, and inhibits the functions of all the nutrient assimilating genes, down-regulated ribulose-1,5-bisphosphate carboxylase/oxygenase II, and cytochrome f genes in P. donghaiense .

HY-W015273A

*trans-3-Indoleacrylic* acid**	Endogenous Metabolite Ferroptosis	Metabolic Disease Cancer
Trans-3-Indoleacrylic acid is a tryptophan metabolite, which promotes tumor development through inhibition of RSL3 (HY-100218A) induced ferroptosis via AHR-ALDH1A3-FSP1-CoQ10 axis, and facilitates colorectal carcinogenesis

HY-W015273S

3-Indoleacrylic acid-d4	Isotope-Labeled Compounds Reactive Oxygen Species	Others
3-Indoleacrylic acid-d₄ is deuterium labeled 3-Indoleacrylic acid. 3-Indoleacrylic acid is a high-efficient antialgal agent. 3-Indoleacrylic acid increases reactive oxygen species (ROS) production, and inhibits the functions of all the nutrient assimilating genes, down-regulated ribulose-1,5-bisphosphate carboxylase/oxygenase II, and cytochrome f genes in P. donghaiense .

*cis-3-Indoleacrylic* acid**	Proton Pump	Others
cis-3-Indoleacrylic acid is a nematicidal compound that can be isolated from Streptomyces youssoufiensis YMF3.862. cis-3-Indoleacrylic acid is also a V‑ATPase inhibitor, and inhibits V-ATPase expression and enzyme activity. cis-3-Indoleacrylic acid causes Meloidogyne incognita juveniles to have swollen bodies with apparent cracks on the cuticle surface (LC₅₀: 16.31 μg/mL). cis-3-Indoleacrylic acid inhibits H ⁺ accumulation in nematode bodies .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W015273A

*trans-3-Indoleacrylic* acid**	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Ferroptosis
Trans-3-Indoleacrylic acid is a tryptophan metabolite, which promotes tumor development through inhibition of RSL3 (HY-100218A) induced ferroptosis via AHR-ALDH1A3-FSP1-CoQ10 axis, and facilitates colorectal carcinogenesis

Cat. No.	Product Name	Chemical Structure

HY-W015273S

3-Indoleacrylic acid-d4
3-Indoleacrylic acid-d₄ is deuterium labeled 3-Indoleacrylic acid. 3-Indoleacrylic acid is a high-efficient antialgal agent. 3-Indoleacrylic acid increases reactive oxygen species (ROS) production, and inhibits the functions of all the nutrient assimilating genes, down-regulated ribulose-1,5-bisphosphate carboxylase/oxygenase II, and cytochrome f genes in P. donghaiense .

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