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ACBI-2

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By Targets:	Epigenetic Reader Domain (1) PROTACs (1)
By Research Areas:	Cancer (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*ACBI2* 1 Publications Verification	PROTACs Epigenetic Reader Domain	Cancer
ACBI2 is a highly potent and orally active VHL PROTAC *SMARCA2* degrader (EC₅₀: 7 nM), which selectively degrades *SMARCA2* with a DC₅₀ value of 1 nM in RKO cells. ACBI2 can be used in the research of lung cancer .

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