ADRB2

By Targets:	Adrenergic Receptor (9) Isotope-Labeled Compounds (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (9) Endocrinology (5)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13338

Mabuterol	Adrenergic Receptor	Cardiovascular Disease
Mabuterol is a selective and orally active **beta-2 adrenergic receptor (ADRB2)** agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB ^[2].

HY-14299

Indacaterol 4 Publications Verification	Adrenergic Receptor	Cardiovascular Disease Endocrinology Cancer
Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol inhibits NF-κB activity in a *β-arrestin2*-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol can also be used in cardiovascular disease research ^[2].

HY-14299A

Indacaterol maleate 4 Publications Verification QAB149	Adrenergic Receptor	Cardiovascular Disease Endocrinology Cancer
Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol maleate inhibits NF-κB activity in a *β-arrestin2*-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research ^[2].

HY-RS00415

ADRB2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ADRB2 Human Pre-designed siRNA Set A contains three designed siRNAs for ADRB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ADRB2 Human Pre-designed siRNA Set A ADRB2 Human Pre-designed siRNA Set A

HY-W755295

Mabuterol hydrochloride	Adrenergic Receptor	Cardiovascular Disease
Mabuterol hydrochloride is a selective and orally active **beta-2 adrenergic receptor (ADRB2)** agonist. Mabuterol hydrochloride inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol hydrochloride suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB ^[2].

HY-14299D

Indacaterol acetate	Adrenergic Receptor	Cardiovascular Disease Endocrinology Cancer
Indacaterol acetate is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol acetate inhibits NF-κB activity in a *β-arrestin2*-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol acetate can also be used in cardiovascular disease research ^[2].

HY-152051S

Mabuterol-d9 hydrochloride	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease
Mabuterol-d₉ (hydrochloride) is deuterium labeled Mabuterol (hydrochloride). Mabuterol hydrochloride is a selective and orally active **beta-2 adrenergic receptor (ADRB2)** agonist. Mabuterol hydrochloride inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol hydrochloride suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB ^[2].

HY-W755295R

Mabuterol hydrochloride (Standard)	Adrenergic Receptor	Cardiovascular Disease
Mabuterol (hydrochloride) (Standard) is the analytical standard of Mabuterol (hydrochloride). This product is intended for research and analytical applications. Mabuterol hydrochloride is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol hydrochloride inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol hydrochloride suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB ^[2].

HY-14299R

Indacaterol (Standard)	Adrenergic Receptor	Cardiovascular Disease Endocrinology Cancer
Indacaterol (Standard) is the analytical standard of Indacaterol. This product is intended for research and analytical applications. Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol inhibits NF-κB activity in a *β-arrestin2*-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol can also be used in cardiovascular disease research ^[2].

HY-14299AR

Indacaterol (maleate) (Standard)	Adrenergic Receptor	Cardiovascular Disease Endocrinology Cancer
Indacaterol (maleate) (Standard) is the analytical standard of Indacaterol (maleate). This product is intended for research and analytical applications. Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol maleate inhibits NF-κB activity in a *β-arrestin2*-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research ^[2].

Species:	Human (2)
Tag:	SUMO (2) His (2)
Source:	E. coli Cell-free (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P702206

	ADRB2 Protein, Human (Cell-Free, His, SUMO) Beta-2 adrenergic receptor; Beta-2 adrenoreceptor; Beta-2 adrenoceptor	Human	E. coli Cell-free
	ADRB2 protein is an important member of the β-adrenergic receptor family and mediates catecholamine-induced adenylyl cyclase activation through G protein action. It has 30 times greater affinity for epinephrine and plays a crucial role in cellular responses to sympathetic nervous system stimulation. ADRB2 Protein, Human (Cell-Free, His, SUMO) is the recombinant human-derived ADRB2 protein, expressed by E. coli Cell-free , with N-6*His, N-SUMO labeled tag and G16R, E27Q mutation. The total length of ADRB2 Protein, Human (Cell-Free, His, SUMO) is 413 a.a., with molecular weight of 65 kDa.

HY-P71530

	PAK1 Protein, Human (His-SUMO) Serine/threonine-protein kinase PAK 1; Alpha-PAK; p21-activated kinase 1 ; p65-PAK; PAK1	Human	E. coli
	PAK1 is a dynamic protein kinase that plays an important role in multiple intracellular signaling pathways, affecting cytoskeletal dynamics, adhesion, migration, proliferation, apoptosis, mitosis, and vesicle trafficking. Multifunctional PAK1 directly phosphorylates BAD to provide antiapoptotic cell protection. PAK1 Protein, Human (His-SUMO) is the recombinant human-derived PAK1 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-152051S

Mabuterol-d9 hydrochloride
Mabuterol-d₉ (hydrochloride) is deuterium labeled Mabuterol (hydrochloride). Mabuterol hydrochloride is a selective and orally active **beta-2 adrenergic receptor (ADRB2)** agonist. Mabuterol hydrochloride inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol hydrochloride suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB ^[2].

Mabuterol-d9 hydrochloride

Mabuterol-d₉ (hydrochloride) is deuterium labeled Mabuterol (hydrochloride). Mabuterol hydrochloride is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol hydrochloride inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol hydrochloride suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB ^[2].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81085

	ADRB2 Antibody Beta 2-adrenergic receptor; beta 2 Adrenergic Receptor; ADRB2R; ADRBR; ADRB2_HUMAN; Adrenergic beta 2 receptor surface; B2AR; BAR; Beta 2 adrenoreceptor; BETA2AR; Catecholamine receptor; beta2-adrenergic receptor. β2-adrenergic receptor	WB, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat
	ADRB2 Antibody is an unconjugated, approximately 46 kDa, rabbit-derived, anti-ADRB2 polyclonal antibody. ADRB2 Antibody can be used for: WB, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, and predicted: dog, rabbit background without labeling.

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Cat. No.	Product Name		Classification

HY-RS00415

ADRB2 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
ADRB2 Human Pre-designed siRNA Set A contains three designed siRNAs for ADRB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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