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AES 135

" in MedChemExpress (MCE) Product Catalog:

By Targets:	HDAC (1)
By Research Areas:	Cancer (1)

Targets Recommended: FLT3

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*AES-135* 1 Publications Verification	HDAC	Cancer
AES-135, a hydroxamic acid-based pan-HDAC inhibitor, prolongs survival in an orthotopic mouse model of pancreatic cancer. AES-135 inhibits HDAC3, HDAC6, HDAC8, and HDAC11 with IC₅₀s ranging from 190-1100 nM .

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