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AMG-510-d<sub>3</sub>

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114277S2
    Sotorasib-d3

    AMG-510-d<sub>3sub>

    		 Isotope-Labeled Compounds Ras Cancer
    Sotorasib-d3 (AMG-510-d3) is deuterium labeled Sotorasib. Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib leads to the regression of KRAS G12C?mutated locally advanced or metastatic non?small cell lung cancer (NSCLC) .
    Sotorasib-d3

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