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Results for "

AQP3

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126073
    DFP00173
    4 Publications Verification

    		 Aquaporin Inflammation/Immunology Cancer
    DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC50 of ∼0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9 .
    DFP00173
  • HY-126074
    Z433927330

    		Aquaporin Others
    Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 µM, ~0.7 µM and ~1.1 µM for mAQP7, mAQP3 and mAQP9, respectively .
    Z433927330
  • HY-B0557
    Bisacodyl

    		Dopamine Transporter Opioid Receptor Metabolic Disease Cancer
    Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect .
    Bisacodyl
  • HY-RS00875
    AQP3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    AQP3 Human Pre-designed siRNA Set A contains three designed siRNAs for AQP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    AQP3 Human Pre-designed siRNA Set A
    AQP3 Human Pre-designed siRNA Set A
  • HY-157979
    AQP3-IN-1

    		Aquaporin Cancer
    AQP3-IN-1 (compounds 3) is an AQP3 inhibitor with a IC50 value of 8.91 μM. AQP3-IN-1 inhibits cell proliferation of melanoma cells .
    AQP3-IN-1
  • HY-142980
    Dioleoylphosphatidylglycerol

    DOPG

    		 Liposome Inflammation/Immunology
    Dioleoylphosphatidylglycerol (DOPG) is a naturally occurring phospholipid that can be produced by the combined action of aquaporin 3 (AQP3) and phospholipase D2 (PLD2). Dioleoylphosphatidylglycerol inhibits macrophage inflammatory mediator production in response to heat shock protein B4 (HSPB4) activation of toll-like receptor 2 (TLR2) .
    Dioleoylphosphatidylglycerol
  • HY-B0557R
    Bisacodyl (Standard)

    		Dopamine Transporter Opioid Receptor Metabolic Disease Cancer
    Bisacodyl (Standard) is the analytical standard of Bisacodyl. This product is intended for research and analytical applications. Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect .
    Bisacodyl (Standard)

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