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Results for "

ARRY-470

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12866
    Larotrectinib
    10+ Cited Publications

    LOXO-101; ARRY-470

    		 Trk Receptor Apoptosis Cancer
    Larotrectinib (LOXO-101) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
    Larotrectinib
  • HY-12866A
    Larotrectinib sulfate
    10+ Cited Publications

    LOXO-101 sulfate; ARRY-470 sulfate

    		 Trk Receptor Apoptosis Cancer
    Larotrectinib sulfate (LOXO-101 sulfate; ARRY-470 sulfate) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
    Larotrectinib sulfate
  • HY-12866B
    (R)-Larotrectinib

    (R)-LOXO-101; (R)-ARRY-470

    		 Trk Receptor Infection Inflammation/Immunology Cancer
    (R)-Larotrectinib is a potent TRK inhibitor with an IC50 value of 28.5 nM for TrkA. (R)-Larotrectinib can be used for researching cancer, inflammatory and certain infectious diseases
    (R)-Larotrectinib