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Results for "

ASD

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Biochemical Assay Reagents

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-113058
    3-Hydroxyoctanoic acid

    		Biochemical Assay Reagents Others
    3-Hydroxyoctanoic acid is a hydroxylated fatty acid that has been found in the LPS of Pseudomonas aeruginosa and in methyl-branched poly(3-hydroxyalkanoate) (PHA) polymers produced by Pseudomonas oleophores. It is an agonist of the orphan receptor GPR109B, increasing intracellular calcium in human neutrophils endogenously expressing GPR109B. 3-Hydroxycaprylic acid prevents lipolysis in human adipocytes and is upregulated in human plasma in response to a ketogenic diet. Plasma levels of 3-hydroxyoctanoic acid were also increased 3.41-fold in human male runners exhausted on a treadmill and in a mouse model of autism spectrum disorder (ASD) fed a high-glycemic diet.
    3-Hydroxyoctanoic acid
  • HY-W142459
    Naphthol AS-D

    		Biochemical Assay Reagents Others
    Naphthol AS-D, in the form of its chloroacetate, can be used to demonstrate the esterase activity of human myeloid cells and contribute to research related to white blood cells .
    Naphthol AS-D
  • HY-163345
    5-HT7R antagonist 2

    		5-HT Receptor Neurological Disease
    5-HT7R antagonist 2 (compound 4h) is a 5-HT7R antagonist that antagonizes the G protein and β-arrestin signaling pathways, with a Ki of 67 nM, the IC50 values in cAMP and Tango tests were 2.59 μM and 39.57 μM, respectively. 5-HT7R antagonist 2 has an effect on neurogenesis and can reduce repetitive behaviors related to autism spectrum disorder (ASD) and restore neurogenesis of ASD impairment .
    5-HT7R antagonist 2
  • HY-131474
    Naphthol AS-D chloroacetate，98% (TLC)

    3-Hydroxy-2-naphthoic-o-toluidide chloroacetate,98% (TLC)

    		 Biochemical Assay Reagents Others
    Naphthol AS-D chloroacetate, 98% (TLC) (3-Hydroxy-2-naphthoic-o-toluidide chloroacetate, 98% (TLC)) is a substrate for esterase histochemical localization.
    Naphthol AS-D chloroacetate，98% (TLC)
  • HY-172318
    IAMA-6

    		NKCC Neurological Disease
    IAMA-6 is a selective NKCC1 inhibitor with neuroprotective effects. IAMA-6 can be used for the study of brain conditions, including drug-resistant epilepsy (e.g. temporal lobe epilepsy (TLE) and Dravet syndrome (DrS)), autism spectrum disorders (ASD) and Down syndrome (DoS) .
    IAMA-6
  • HY-138830A
    (S,S)-TAK-418

    		Histone Demethylase Neurological Disease
    (S,S)-TAK-418 is a potent inhibitor of lysine-specific demethylase 1 (LSD1), demonstrating significant normalization of aberrant gene expression in neurodevelopmental disorders. (S,S)-TAK-418 also ameliorates ASD-like behaviors in rodent models affected by maternal exposure to valproate or poly I:C. (S,S)-TAK-418 modulates gene expression differently across various models and ages, indicating its potential as a therapeutic agent for conditions like autism spectrum disorder and schizophrenia.
    (S,S)-TAK-418

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