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ASR-490

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Notch (1)
By Research Areas:	Cancer (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*ASR-490*	Notch	Cancer
ASR-490 reduces the viability of HCT116 and SW620 cells by downregulating Notch1 signaling. ASR-490 overcomes Notch1 overexpression and inhibits the growth of HCT/Notch1 transfectants. ASR-490 inhibits the tumor growth in control (pCMV/HCT116) and Notch1/HCT116 in xenotransplanted mice .

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