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Akt1-IN-8

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-173122
    Akt1-IN-8

    		Akt Cancer
    Akt1-IN-8 (Compound JL18) is a potent and oral bioavailable (41%) inhibitor of AKT1 kinase, with an IC50 of 8.8 nM. Akt1-IN-8 exhibits significant antiproliferative effects against PC-3 prostate cancer cells, with an IC50 of 3.0 μM. Akt1-IN-8 can reduce phosphorylated GSK3β levels .
    Akt1-IN-8

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