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Pathways Recommended: Antibody-drug Conjugate/ADC Related
Results for "

Anti-CD33 Antibody

" in MedChemExpress (MCE) Product Catalog:

1

Inhibitors & Agonists

2

Inhibitory Antibodies

Cat. No. Product Name Target Research Area
  • HY-P9983

    HuM-195

    Transmembrane Glycoprotein Radionuclide-Drug Conjugates (RDCs) Inflammation/Immunology
    Lintuzumab (HUM-195) is an anti-CD33 humanized monoclonal antibody. Lintuzumab reduces the production of TNFα-induced pro-inflammatory cytokines and chemokines by AML cells. Lintuzumab promotes tumor cell killing through antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis (ADCP) activities against MDR and MDR+ AML cell lines and primary AML patient samples. Lintuzumab enhances survival and reduces tumor burden in mice .
  • HY-P990605

    IMGN-779 Antibody

    Inhibitory Antibodies Inflammation/Immunology
    Anti-CD33 Antibody (IMGN-779 antibody) is a CHO-expressed humanized antibody targeting Siglec-3/CD33. Anti-CD33 Antibody carries a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.6 kDa. The isotype control for Anti-CD33 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

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