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Anti-inflammatory agent 93

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-159719
    Anti-inflammatory agent 93

    		NF-κB Inflammation/Immunology
    Anti-inflammatory agent 93 (Compound 3q) is a potent cholinergic anti-inflammatory pathway (CAP) activators. Anti-inflammatory agent 93 inhibits Monosodium urate (MSU) (HY-B2130A)-induced IL-1β production in THP-1 cells, indicating its potential against gout arthritis. Anti-inflammatory agent 93 inhibits MSU induced phosphorylation of NF-κB p65, without any inhibitory effect against NLRP3, pro-caspase 1, or the self-cleavage and activation of caspase-1 of the second signaling. Therefore, Anti-inflammatory agent 93 inhibits the initial phase of NLRP3 through CAP activation .
    Anti-inflammatory agent 93

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