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Results for "

Antidiabetic Agent

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Aldose Reductase (2) AMPK (7) Amylases (4) Amylin Receptor (3) Antibiotic (4) Apoptosis (4) Autophagy (3) Bacterial (3) Dipeptidyl Peptidase (2) Endogenous Metabolite (4) Fatty Acid Synthase (FASN) (2) Glucosidase (5) GLUT (1) HSP (1) Interleukin Related (1) Isotope-Labeled Compounds (3) MAP4K (1) Mitochondrial Metabolism (2) NF-κB (2) PARP (2) Phosphatase (3) Potassium Channel (5) PPAR (3) Reactive Oxygen Species (1) SGLT (5) Thyroid Hormone Receptor (1)
By Research Areas:	Cancer (24) Cardiovascular Disease (1) Infection (5) Inflammation/Immunology (6) Metabolic Disease (54)
Oligonucleotides:	Cholesterol (1)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-109144

Enavogliflozin DWP-16001	SGLT	Metabolic Disease
Enavogliflozin (DWP-16001), an antidiabetic agent, is an orally active, best-in-class and selective sodium-glucose cotransporter-2 (SGLT-2) inhibitor .

HY-B2099A

Buformin hydrochloride 3 Publications Verification 1-Butylbiguanide hydrochloride	AMPK	Cancer
Buformin hydrochloride (1-Butylbiguanide hydrochloride), a potent AMPK activator, acts as an orally active biguanide **antidiabetic agent*. Buformin hydrochloride decreases hepatic gluconeogenesis and lowers blood glucose production in vivo. Buformin hydrochloride also has anti*-cancer activities and is applied in cancer study (such as, cervical cancer and breast cancer, et al) .

HY-16397A

Phenformin hydrochloride 5+ Cited Publications Phenethylbiguanide hydrochloride	AMPK Autophagy	Cancer
Phenformin hydrochloride is an anti-diabetic agent from the biguanide class, can activate AMPK activity.

HY-161429

Antidiabetic agent 5	Amylases Glucosidase	Metabolic Disease
Antidiabetic agent 5 (compound S1) is a antidiabetic agent. Antidiabetic agent 5 inhibits the activity of α-glucosidase and α-amylase with IC₅₀ values of 3.91, 8.89 µM, respectively. Antidiabetic agent 5 decreases sugar levels. Antidiabetic agent 5 has the potential for the research of type-II diabetes .

HY-163853

Antidiabetic agent 6	GLUT Akt	Metabolic Disease
Antidiabetic agent 6 (Compound 19) is an antidiabetic Agent. Antidiabetic agent 6 stimulates GLUT4 translocation by activation of the PI3K/AKT-dependent signaling pathway. Antidiabetic agent 6 reduces blood glucose levels in Streptozotocin (HY-13753)-induced diabetic rats .

HY-155961

Antidiabetic agent 2	Dipeptidyl Peptidase Phosphatase Amylases Glucosidase	Metabolic Disease
Antidiabetic agent 2 (Compound 56) is a glucose-uptake promoter. Antidiabetic agent 2 inhibits DPP-4, PTP-1B, α-amylase, and α-glucosidase with IC₅₀s of 0.036, 0.042, 0.241, 0.185 μM. Antidiabetic agent 2 decreases blood glucose levels .

HY-B2099

Buformin 1-Butylbiguanide	AMPK	Metabolic Disease Cancer
Buformin (1-Butylbiguanide), a potent AMPK activator, acts as an orally active biguanide **antidiabetic agent*. Buformin decreases hepatic gluconeogenesis and lowers blood glucose production in vivo. Buformin also has anti*-cancer activities and is applied in cancer study (such as, cervical cancer and breast cancer, et al) .

HY-121731

Nimbocinone	Others	Metabolic Disease
Nimbocinone, isolated from Azadirachta indica, exhibits antidiabetogenic activity .

HY-101758

BM-131246	Others	Metabolic Disease
BM-131246 is an oral antidiabetic agent.

HY-120401

Glybuzole Desaglybuzole	Others	Metabolic Disease
Glybuzole (Desaglybuzole) is an orally active hypoglycaemic agent that has antidiabetic effect .

HY-P0058

Pramlintide	Amylin Receptor	Metabolic Disease Cancer
Pramlintide is a polypeptide analogue of human amylin. Pramlintide, an antidiabetic agent, is antineoplastic in colorectal cancer .

HY-P0058B

Pramlintide acetate	Amylin Receptor	Metabolic Disease Cancer
Pramlintide acetate is a polypeptide analogue of human amylin. Pramlintide acetate, an antidiabetic agent, is antineoplastic in colorectal cancer .

HY-15516

Sotagliflozin Maximum Cited Publications 11 Publications Verification LX-4211; LP-802034	SGLT	Metabolic Disease
Sotagliflozin (LX-4211) is a potent dual SGLT2/1 inhibitor. Antidiabetic agents.

HY-17451

Glibornuride	Potassium Channel	Metabolic Disease
Glibornuride is a blocker of ATP-sensitive K ⁺ channels (K_ATP channel) with a pK_i of 5.75 . Antidiabetic agent .

HY-P0058A

Pramlintide TFA	Amylin Receptor	Metabolic Disease Cancer
Pramlintide TFA is a polypeptide analogue of human amylin. Pramlintide TFA, an antidiabetic agent, is antineoplastic in colorectal cancer .

HY-W041324

Glimepiride sulfonamide	Others	Infection
Glimepiride sulfonamide is a intermediate, and can be used to synthesize Glimepiride (HY-B0104) (antidiabetic agent) .

HY-B1114

Gliquidone AR-DF 26	Others	Metabolic Disease
Gliquidone (AR-DF 26) is an anti-diabetic agent in the sulfonylurea class, used in the treatment of diabetes mellitus type 2.

HY-168621

DPP-4-IN-13	Dipeptidyl Peptidase	Metabolic Disease
DPP-4-IN-13 (compound 9i) is a competitive DPP4 inhibitor with the IC₅₀ of 9.25 μM and can be used for study of type 2 diabetes .

HY-16397AS

Phenformin-d5 hydrochloride Phenethylbiguanide-d₅ hydrochloride	Isotope-Labeled Compounds AMPK Autophagy	Cancer
Phenformin-d₅ (hydrochloride) is the deuterium labeled Phenformin hydrochloride. Phenformin hydrochloride is an anti-diabetic agent from the biguanide class, can activate AMPK activity[1][2].

HY-131504A

Valienamine	Glucosidase	Metabolic Disease
Valienamine is the alpha-glucosidase inhibitor. Valienamine is the key functional component of many natural glycosidase inhibitors including the crop protectant validamycin A and the antidiabetic agent acarbose .

HY-16397AR

Phenformin hydrochloride (Standard)	AMPK Autophagy	Cancer
Phenformin (hydrochloride) (Standard) is the analytical standard of Phenformin (hydrochloride). This product is intended for research and analytical applications. Phenformin hydrochloride is an anti-diabetic agent from the biguanide class, can activate AMPK activity.

HY-B1114S

Gliquidone-d6 AR-DF 26-d₆	Isotope-Labeled Compounds	Metabolic Disease
Gliquidone-d₆ is deuterium labeled Gliquidone. Gliquidone (AR-DF 26) is an anti-diabetic agent in the sulfonylurea class, used in the treatment of diabetes mellitus type 2.

HY-126198

Linogliride McN-3935	Antibiotic	Metabolic Disease
Linogliride (MCN-3935) is an antidiabetic agent. Linogliride (100 μM) does not affect insulin secretion in the absence of glucose, but has a significant insulinotropic effect in the presence of 5.5 mM glucose .

HY-126198A

Linogliride fumarate McN-3935 fumarate	Antibiotic	Metabolic Disease
Linogliride (MCN-3935) fumarate is an antidiabetic agent. Linogliride fumarate (100 μM) does not affect insulin secretion in the absence of glucose, but has a significant insulinotropic effect in the presence of 5.5 mM glucose .

HY-17451R

Glibornuride (Standard)	Potassium Channel	Metabolic Disease
Glibornuride (Standard) is the analytical standard of Glibornuride. This product is intended for research and analytical applications. Glibornuride is a blocker of ATP-sensitive K+ channels (KATP channel) with a pKi of 5.75 . Antidiabetic agent .

HY-B1114R

Gliquidone (Standard)	Others	Metabolic Disease
Gliquidone (Standard) is the analytical standard of Gliquidone. This product is intended for research and analytical applications. Gliquidone (AR-DF 26) is an anti-diabetic agent in the sulfonylurea class, used in the treatment of diabetes mellitus type 2.

HY-115978

α-Glucosidase-IN-2	Glucosidase	Metabolic Disease
α-Glucosidase-IN-2 (compound 5d) is a potent α-Glucosidase inhibitor with an IC₅₀ of 9.48 µM. α-Glucosidase-IN-2 is an antidiabetic agent .

HY-161782

α-Amylase-IN-7	Amylases	Metabolic Disease
α-Amylase-IN-7 (Compound 6e) is an inhibitor for α-Amylase with an IC₅₀ of 40 μM. α-Amylase-IN-7 exhibits potential as an antidiabetic agent .

HY-W041324R

Glimepiride sulfonamide (Standard)	Others	Infection
Glimepiride sulfonamide (Standard) is the analytical standard of Glimepiride sulfonamide. This product is intended for research and analytical applications. Glimepiride sulfonamide is a intermediate, and can be used to synthesize Glimepiride (HY-B0104) (antidiabetic agent) .

HY-N7912

Pterosin A (2S)-Pterosin A	Others	Metabolic Disease
Pterosin A is an orally active anti-diabetic agent. Pterosin A promotes glucose uptake, increases serum insulin, and improves hyperglycemia and glucose intolerance in diabetic mice. Pterosin A can be isolated from Pteridium aquilinum .

HY-130289

(±)4-HDHA 4-Hydroxy docosahexaenoic acid; (±)4-HDoHE	PPAR	Metabolic Disease Inflammation/Immunology
(±)4-HDHA (4-Hydroxy docosahexaenoic acid) is an autoxidation product of Docosahexaenoic acid (HY-B2167) (DHA). (±)4-HDHA is a PPARγ agonist, antidiabetic and anti-inflammatory agent .

HY-115940

Aldose reductase-IN-2	Aldose Reductase	Metabolic Disease
Aldose reductase-IN-2 (Compound 5f) is a potent inhibitor of aldose reductase (AR). Aldose reductase-IN-2 has antioxidation capacity. Aldose reductase-IN-2 is a promising anti-diabetic complications agent .

HY-B0401A

Tolbutamide sodium	Apoptosis	Metabolic Disease Cancer
Tolbutamide sodium is a potent and orally active *antidiabetic* agent. Tolbutamide sodium induces apoptosis in a Ca ²⁺ dependent manner in pancreatic β-cells. Tolbutamide sodium has the potential for the research of non-insulin-dependent diabetes mellitus .

HY-122083

T2384	PPAR	Metabolic Disease
T2384 is a peroxisome proliferator-activated receptor γ (PPARγ) ligand. T2384 also is an orally active antidiabetic agent. T2384 reduces the fasting plasma glucose levels and plasma insulin levels .

HY-125012

MAP4K4-IN-3 1 Publications Verification	MAP4K	Metabolic Disease
MAP4K4-IN-3 (Compound 17) is a potent and selective MAP4K4 inhibitor with an IC₅₀ of 14.9 nM in kinase assay, an IC₅₀ of 470 nM in cell assay. Antidiabetic agent .

HY-N2486

Desoxyrhaponticin 1 Publications Verification	Fatty Acid Synthase (FASN) Apoptosis	Cancer
Desoxyrhaponticin is a kind of oral drug that inhibits effective fatty acid synthesis (FASN), and has a fatal effect on cancer cells. Desoxyrhaponticin has the ability to inhibit glucose uptake, improve oral glucose tolerance as a diabetic agent, and possess anti-diabetic effects .

HY-W012634

Benzothiazole	Bacterial	Infection Metabolic Disease Inflammation/Immunology Cancer
Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent ^[1][2][3][4].

HY-N2413

Gomisin D	Others	Metabolic Disease
Gomisin D, a lignan compound isolated from Fructus Schisandra, is a potential antidiabetic and anti-Alzheimer’s agent. Gomisin D inhibits UDP-Glucuronosyltransferases activity and scavenges ABTS(+) radicals. Gomisin D is used as a quality marker of Shengmai San and shenqi Jiangtang Granule .

HY-134769

OPC-163493	Mitochondrial Metabolism Reactive Oxygen Species	Cardiovascular Disease Metabolic Disease
OPC-163493 is an orally active and liver-targeted mitochondrial uncoupling agent. OPC-163493 reduces the production of mitochondrial Δψ and ROS. OPC-163493 has anti-diabetic and lipid-lowering effects. In addition, OPC-163493 has a protective effect on cardiovascular disease .

HY-163899

(+)-Crinatusin A1	Phosphatase	Metabolic Disease
(+)-Crinatusin A1 (Compound (+)- 4) is a chalcone-monoterpene hybrid, which can be isolated from Cleistocalyx operculatus. (+)-Crinatusin A1 is an inhibitor for protein tyrosine phosphatase 1B (PTP1B) with IC₅₀ of 0.9 μM. (+)-Crinatusin A1 exhibits potential as an antidiabetic agent .

HY-B0254

Glipizide CP 28720; K 4024	Potassium Channel	Metabolic Disease Cancer
Glipizide (CP 2872; K 4024)?a potent, orally active and sulfonylurea class *anti-diabetic* agent and can be used for type 2?diabetes mellitus research but not type 1. Glipizide acts by partially blocking ATP-sensitive potassium?(K_ATP) channels among β cells of pancreatic islets of Langerhans .

HY-14894

Ipragliflozin 5+ Cited Publications ASP1941	SGLT	Metabolic Disease
Ipragliflozin (ASP1941) is an orally active and selective SGLT2 inhibitor with IC₅₀s of 7.38 and 1876 nM, 6.73 and 1166 nM, 5.64 and 1380 nM for human SGLT2 and SGLT1, rat SGLT2 and SGLT1, mouse SGLT2 and SGLT1, respectively. Antidiabetic agent .

HY-152158

α-Glucosidase-IN-22	Glucosidase	Metabolic Disease
α-Glucosidase-IN-22 (compound 7i), a benzimidazole, is a potent α-glucosidase inhibitor with an IC₅₀ of 0.64 μM. α-Glucosidase-IN-22 is a potent anti-diabetic agent and has the potential for type 2 diabetes mellitus (T2DM) research .

HY-16397

Phenformin 5+ Cited Publications Phenethylbiguanide	Mitochondrial Metabolism AMPK Apoptosis	Metabolic Disease Cancer
Phenformin (1-phenethylbiguanide) is an orally active antidiabetic and anticancer agent. Phenformin has an incidence of associated lactic acidosis. Phenformin acts through acting AMPK activation and blocking mTOR pathway. Phenformin is also a substrate of P-glycoprotein (P-gp), and an OXPHOS inhibitor. Phenformin induces cancer cell apoptosis .

HY-N11844

Quercetin 3-(6″-caffeoylsophoroside)	Amylases	Metabolic Disease
Quercetin 3-(6″-caffeoylsophoroside) is an orally active α-amylase inhibitor, with an IC₅₀ of 73.66 μg/mL. Quercetin 3-(6″-caffeoylsophoroside) presents in thehydro-methanolic extract of Cardamine hirsuta Linn. Quercetin 3-(6″-caffeoylsophoroside) shows the antidiabetic activities by oxidative stress reduction and α-amylase inhibition. Quercetin 3-(6″-caffeoylsophoroside) can be used for diabetes mellitus research .

HY-14621

Zingerone 4 Publications Verification Vanillylacetone; Gingerone	NF-κB	Metabolic Disease Inflammation/Immunology Cancer
Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties . Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways . Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells .

HY-N12353

Stevisalioside A	Phosphatase	Metabolic Disease
Stevisalioside A (Compound 2) can be isolated from Stevia serrata roots. Stevisalioside A is an orally active antidiabetic agent. Stevisaliosides A inhibits PTP1B (IC₅₀: 526.8 μM). Stevisalioside A reduces blood glucose levels and the postprandial peak in oral glucose and insulin tolerance tests in Streptozotocin (HY-13753) induced hyperglycemic mice .

HY-N2486R

Desoxyrhaponticin (Standard)	Fatty Acid Synthase (FASN) Apoptosis	Cancer
Desoxyrhaponticin (Standard) is the analytical standard of Desoxyrhaponticin. This product is intended for research and analytical applications. Desoxyrhaponticin is a kind of oral drug that inhibits effective fatty acid synthesis (FASN), and has a fatal effect on cancer cells. Desoxyrhaponticin has the ability to inhibit glucose uptake, improve oral glucose tolerance as a diabetic agent, and possess anti-diabetic effects .

HY-W012634R

Benzothiazole (Standard)	Bacterial	Infection Metabolic Disease Inflammation/Immunology Cancer
Benzothiazole (Standard) is the analytical standard of Benzothiazole. This product is intended for research and analytical applications. Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent .

HY-42680

D-Tagatose D-(-)-Tagatose	Endogenous Metabolite	Metabolic Disease Cancer
D-Tagatose (D-(-)-Tagatose) is a rare monosaccharide found in nature with prebiotic characteristics. D-Tagatose is as a substitute for sucrose and a low-calorie sweetener in foodstuffs such as gum, fruit juice, and beverages. D-Tagatose is also a potential antidiabetic agent for the research of type II diabetes and a prebiotic to help elevate beneficial bacteria in the colon, prevent colon cancer, and lower cholesterol .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7912

Pterosin A (2S)-Pterosin A	Pteridium aquilinum (L.) Kuhn Structural Classification Natural Products Source classification Plants Pteridiaceae	Others
Pterosin A is an orally active anti-diabetic agent. Pterosin A promotes glucose uptake, increases serum insulin, and improves hyperglycemia and glucose intolerance in diabetic mice. Pterosin A can be isolated from Pteridium aquilinum .

HY-N2486

Desoxyrhaponticin 1 Publications Verification	Structural Classification Monophenols Stilbenes Classification of Application Fields Polygonaceae Source classification Rheum rhabarbarum Linnaeus Phenols Plants Rheum tanguticum Disease Research Fields Cancer	Fatty Acid Synthase (FASN) Apoptosis
Desoxyrhaponticin is a kind of oral drug that inhibits effective fatty acid synthesis (FASN), and has a fatal effect on cancer cells. Desoxyrhaponticin has the ability to inhibit glucose uptake, improve oral glucose tolerance as a diabetic agent, and possess anti-diabetic effects .

HY-W012634

Benzothiazole	Microorganisms Source classification	Bacterial
Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent ^[1][2][3][4].

HY-N2413

Gomisin D	Classification of Application Fields Source classification Lignans Metabolic Disease Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill.	Others
Gomisin D, a lignan compound isolated from Fructus Schisandra, is a potential antidiabetic and anti-Alzheimer’s agent. Gomisin D inhibits UDP-Glucuronosyltransferases activity and scavenges ABTS(+) radicals. Gomisin D is used as a quality marker of Shengmai San and shenqi Jiangtang Granule .

HY-14621

Zingerone 4 Publications Verification Vanillylacetone; Gingerone	Structural Classification Classification of Application Fields Source classification Metabolic Disease Plants Zingiber officinale Roscoe Monophenols Microorganisms Ketones, Aldehydes, Acids Phenols Inflammation/Immunology Disease Research Fields Zingiberaceae	NF-κB
Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties . Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways . Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells .

HY-121731

Nimbocinone	Triterpenes Structural Classification Terpenoids Source classification Plants Azadirachta indica A. Juss. Meliaceae	Others
Nimbocinone, isolated from Azadirachta indica, exhibits antidiabetogenic activity .

HY-163899

(+)-Crinatusin A1	Structural Classification Other Monoterpenes Terpenoids Source classification Myrtaceae Plants Syzygium nervosum Candolle	Phosphatase
(+)-Crinatusin A1 (Compound (+)- 4) is a chalcone-monoterpene hybrid, which can be isolated from Cleistocalyx operculatus. (+)-Crinatusin A1 is an inhibitor for protein tyrosine phosphatase 1B (PTP1B) with IC₅₀ of 0.9 μM. (+)-Crinatusin A1 exhibits potential as an antidiabetic agent .

HY-N11844

Quercetin 3-(6″-caffeoylsophoroside)	Structural Classification Natural Products Cardamine hirsuta L. Source classification Plants Brassicaceae	Amylases
Quercetin 3-(6″-caffeoylsophoroside) is an orally active α-amylase inhibitor, with an IC₅₀ of 73.66 μg/mL. Quercetin 3-(6″-caffeoylsophoroside) presents in thehydro-methanolic extract of Cardamine hirsuta Linn. Quercetin 3-(6″-caffeoylsophoroside) shows the antidiabetic activities by oxidative stress reduction and α-amylase inhibition. Quercetin 3-(6″-caffeoylsophoroside) can be used for diabetes mellitus research .

HY-N12353

Stevisalioside A	Structural Classification Isodon hispidus (Bentham) Murata Polysaccharides Source classification Plants Compositae Saccharides	Phosphatase
Stevisalioside A (Compound 2) can be isolated from Stevia serrata roots. Stevisalioside A is an orally active antidiabetic agent. Stevisaliosides A inhibits PTP1B (IC₅₀: 526.8 μM). Stevisalioside A reduces blood glucose levels and the postprandial peak in oral glucose and insulin tolerance tests in Streptozotocin (HY-13753) induced hyperglycemic mice .

HY-N2486R

Desoxyrhaponticin (Standard)	Structural Classification Monophenols Stilbenes Polygonaceae Source classification Rheum rhabarbarum Linnaeus Phenols Plants Rheum tanguticum	Fatty Acid Synthase (FASN) Apoptosis
Desoxyrhaponticin (Standard) is the analytical standard of Desoxyrhaponticin. This product is intended for research and analytical applications. Desoxyrhaponticin is a kind of oral drug that inhibits effective fatty acid synthesis (FASN), and has a fatal effect on cancer cells. Desoxyrhaponticin has the ability to inhibit glucose uptake, improve oral glucose tolerance as a diabetic agent, and possess anti-diabetic effects .

HY-W012634R

Benzothiazole (Standard)	Microorganisms Source classification	Bacterial
Benzothiazole (Standard) is the analytical standard of Benzothiazole. This product is intended for research and analytical applications. Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent .

HY-42680

D-Tagatose D-(-)-Tagatose	Structural Classification Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Sweeteners Saccharides Monosaccharides Food Research	Endogenous Metabolite
D-Tagatose (D-(-)-Tagatose) is a rare monosaccharide found in nature with prebiotic characteristics. D-Tagatose is as a substitute for sucrose and a low-calorie sweetener in foodstuffs such as gum, fruit juice, and beverages. D-Tagatose is also a potential antidiabetic agent for the research of type II diabetes and a prebiotic to help elevate beneficial bacteria in the colon, prevent colon cancer, and lower cholesterol .

HY-N6883

6-Methoxytricin	Flavonoids other families Classification of Application Fields Flavones Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields	Aldose Reductase
6-Methoxytricin (Compound 6) is an flavonoid isolated from Artemisia iwayomogi. 6-Methoxytricin (Compound 6) is an inhibitor on aldose reductase (AR) and advanced glycation endproduct (AGE) formation activities with IC₅₀ values of 30.29 μM and 134.88 μM, respectively. 6-Methoxytricin (Compound 6) has potential as an anti-diabetic complications agent .

HY-N4103

Fucosterol	Structural Classification other families Classification of Application Fields Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields Steroids	PARP Endogenous Metabolite
Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities . Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research .

HY-14621R

Zingerone (Standard)	Zingiber officinale Roscoe Structural Classification Monophenols Microorganisms Ketones, Aldehydes, Acids Source classification Phenols Plants Zingiberaceae	NF-κB
Zingerone (Standard) is the analytical standard of Zingerone. This product is intended for research and analytical applications. Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties . Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways . Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells .

HY-N4103R

Fucosterol (Standard)	Structural Classification other families Classification of Application Fields Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields Steroids	PARP Endogenous Metabolite
Fucosterol (Standard) is the analytical standard of Fucosterol. This product is intended for research and analytical applications. Fucosterol is a sterol isolated from algae, seaweed or diatoms.?Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities . Fucosterol regulates adipogenesis via inhibition of?PPARα?and?C/EBPα?expression and can be used for anti-obesity agents development research .

HY-42680R

D-Tagatose (Standard)	Structural Classification Microorganisms Source classification Endogenous metabolite Saccharides Monosaccharides	Endogenous Metabolite
D-Tagatose (Standard) is the analytical standard of D-Tagatose. This product is intended for research and analytical applications. D-Tagatose (D-(-)-Tagatose) is a rare monosaccharide found in nature with prebiotic characteristics. D-Tagatose is as a substitute for sucrose and a low-calorie sweetener in foodstuffs such as gum, fruit juice, and beverages. D-Tagatose is also a potential antidiabetic agent for the research of type II diabetes and a prebiotic to help elevate beneficial bacteria in the colon, prevent colon cancer, and lower cholesterol .

HY-B1350A

Fusidic acid sodium salt 2 Publications Verification Sodium fusidate; SQ-16360	Infection Triterpenes Structural Classification Microorganisms Classification of Application Fields Terpenoids Source classification Disease Research Fields Cancer	Bacterial Antibiotic Interleukin Related
Fusidic acid sodium salt is an orally available antibacterial agent that inhibits bacterial protein synthesis by preventing the release of translation elongation factor G (EF-G) from ribosomes. Fusidic acid sodium salt inhibits the inhibitory and activating effects of interleukins IL-1 and IL-6 on glucose-induced insulin production and exhibits antidiabetic effects in a rat model. Fusidic acid sodium salt improves the symptoms of colitis in rats and inhibits the growth of Toxoplasma gondii and Listeria monocytogenes EGD in vitro, but not in mice .

Cat. No.	Product Name	Chemical Structure

HY-16397AS

Phenformin-d5 hydrochloride
Phenformin-d₅ (hydrochloride) is the deuterium labeled Phenformin hydrochloride. Phenformin hydrochloride is an anti-diabetic agent from the biguanide class, can activate AMPK activity[1][2].

HY-B1114S

Gliquidone-d6
Gliquidone-d₆ is deuterium labeled Gliquidone. Gliquidone (AR-DF 26) is an anti-diabetic agent in the sulfonylurea class, used in the treatment of diabetes mellitus type 2.

HY-B2099S

Buformin-d9 hydrochloride
Buformin-d₉ (hydrochloride) is the deuterium labeled Buformin. Buformin (1-Butylbiguanide), a potent AMPK activator, acts as an orally active biguanide antidiabetic agent. Buformin decreases hepatic gluconeogenesis and lowers blood glucose production in vivo. Buformin also has anti-cancer activities and is applied in cancer study (such as, cervical cancer and breast cancer, et al)[1].

HY-B0254S

Glipizide-d11
Glipizide-d₁₁ is the deuterium labeled Glipizide. Glipizide (CP 2872; K 4024) a potent, orally active and sulfonylurea class anti-diabetic agent and can be used for type 2 diabetes mellitus research but not type 1. Glipizide acts by partially blocking ATP-sensitive potassium (KATP) channels among β cells of pancreatic islets of Langerhans[1][2].

Cat. No.	Product Name		Classification

HY-N4103

Fucosterol		Cholesterol
Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities . Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research .

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Antidiabetic Agent

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Peptides

NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

Natural
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