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Atg4B

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Atg4 (6) Autophagy (6) Cathepsin (2) E1/E2/E3 Enzyme (1) Phospholipase (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (6) Inflammation/Immunology (1)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

9

Inhibitors & Agonists

2

Antibodies

2

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Atg4B-IN-2	Atg4 Cathepsin Phospholipase Autophagy	Cancer
Atg4B-IN-2 is a potent competitive *Atg4B* inhibitor with K_i value of 3.1 μM, also possesses declining PLA₂ inhibitory potency, IC₅₀s of 11 μM and 3.5 μM for Atg4B and PLA₂, respectively. Atg4B-IN-2 enhances the anticancer activity of anti-castration-resistant prostate cancer agents via autophagy inhibition .

STK683963	Atg4 Autophagy	Cancer
STK683963 is a strong activator of cellular *ATG4B* activity. STK683963 can act as a mediator of redox-regulation of ATG4B in cells. STK683963 can be used for the research of cancer .

NSC 185058	Autophagy Atg4	Cancer
NSC 185058 is an inhibitor of *ATG4B, a major cysteine protease. Inhibition of ATG4*B using NSC 185058 markedly attenuates autophagic activity .

LV-320	Atg4 Autophagy	Cancer
LV-320 is a potent and uncompetitive *ATG4B* inhibitor with an IC₅₀ of 24.5 μM and a K_d of 16 μM. LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic and active in vivo .

S130	Atg4 Cathepsin Autophagy Apoptosis	Cancer
S130 is a high affinity, selective inhibitor of *ATG4B* (a major cysteine protease) with an IC₅₀ of 3.24 µM. S130 suppresses autophagy flux .

ATG4B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ATG4B Human Pre-designed siRNA Set A contains three designed siRNAs for ATG4B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ATG4B Human Pre-designed siRNA Set A ATG4B Human Pre-designed siRNA Set A

Atg4b Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)
Atg4b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atg4b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Atg4b Mouse Pre-designed siRNA Set A Atg4b Mouse Pre-designed siRNA Set A

MJO445	Atg4 Autophagy	Cancer
MJO445 (Compound 7) is a *ATG4B* inhibitor, which inhibits the autophagy of glioblastoma .

RNF5 agonist 1	E1/E2/E3 Enzyme	Inflammation/Immunology
RNF5 agonist 1 (analog-1), a structural analog of RNF5 inhibitor inh-02 (HY-123967), is a potent RNF5 agonist. RNF5 agonist 1 increases the ubiquitylation status of ATG4B in F508del-CFTR-expressing CFBE41o- cells .

Cat. No.	Compare	Product Name	Application	Reactivity

	ATG4B Antibody (YA2468) Atg4B; APG4B; AUTL1; KIAA0943; Cysteine protease Atg4B; AUT-like 1 cysteine endopeptidase; Autophagin-1; Autophagy-related cysteine endopeptidase 1; Autophagy-related protein 4 homolog B; hAPG4B	WB, FC	Human, Mouse, Rat
	ATG4B Antibody (YA2468) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2468), targeting ATG4B, with a predicted molecular weight of 44 kDa (observed band size: 44 kDa). ATG4B Antibody (YA2468) can be used for WB, FC experiment in human, mouse, rat background.

	ATG4B Antibody (YA3461) Atg4B; APG4B; AUTL1; KIAA0943; Cysteine protease Atg4B; AUT-like 1 cysteine endopeptidase; Autophagin-1; Autophagy-related cysteine endopeptidase 1; Autophagy-related protein 4 homolog B; hAPG4B	WB, FC, ELISA	Human, Mouse
	ATG4B Antibody (YA3461) is a mouse-derived non-conjugated IgG antibody (Clone NO.: YA3461), targeting ATG4B, with a predicted molecular weight of 44 kDa (observed band size: 44 kDa). ATG4B Antibody (YA3461) can be used for WB, FC, ELISA experiment in human, mouse background.

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