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BIIE 0246

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101986
    BIIE-0246
    1 Publications Verification

    AR-H 053591

    		 Neuropeptide Y Receptor Metabolic Disease Endocrinology
    BIIE-0246 (AR-H 053591) is a potent and selective NPY2R (neuropeptide Y receptor 2) antagonist with an IC50 value of 15 nM for rat [ 125I]PYY3-36. BIIE-0246 decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 reduces albuminuria in ADR nephropathy .
    BIIE-0246
  • HY-101986A
    BIIE-0246 hydrochloride
    1 Publications Verification

    AR-H 053591 hydrochloride

    		 Neuropeptide Y Receptor Metabolic Disease
    BIIE-0246 hydrochloride (AR-H 053591 hydrochloride) is a potent and selective NPY2R (neuropeptide Y receptor 2) antagonist with an IC50 value of 15 nM for rat [ 125I]PYY3-36. BIIE-0246 hydrochloride decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 hydrochloride reduces albuminuria in ADR nephropathy .
    BIIE-0246 hydrochloride
  • HY-101986C
    BIIE-0246 dihydrochloride

    AR-H 053591 dihydrochloride

    		 Neuropeptide Y Receptor Neurological Disease
    BIIE-0246 dihydrochloride (AR-H 053591 dihydrochloride) is a potent and highly selective non-peptide neuropeptide Y (NPY) Y2 receptor antagonist, with an IC50 value of 15 nM .
    BIIE-0246 dihydrochloride

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