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Results for "

BMS1

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-19991
    BMS-1
    20+ Cited Publications

    PD-1/PD-L1 inhibitor 1

    		 PD-1/PD-L1 Apoptosis Inflammation/Immunology Cancer
    BMS-1 is an inhibitor of the PD-1/PD-L1 protein/protein interaction (IC50 between 6 and 100 nM) [1] .
    BMS-1
  • HY-RS01555
    BMS1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    BMS1 Human Pre-designed siRNA Set A contains three designed siRNAs for BMS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    BMS1 Human Pre-designed siRNA Set A
    BMS1 Human Pre-designed siRNA Set A
  • HY-19991A
    (Rac)-BMS-1

    		Ligands for Target Protein for PROTAC PD-1/PD-L1 Cancer
    (Rac)-BMS-1 is a racemate of BMS-1 (HY-19991A). (Rac)-BMS-1 can be used as a target protein ligand to synthesize D5B PROTAC (HY-169392) [1].
    (Rac)-BMS-1
  • HY-169434
    LTB

    Lon-TK-BMS-1

    		 PD-1/PD-L1 Cancer
    LTB is a prodrug formed by coupling glycolysis inhibitor (Lonidamine (HY-B0486)) with PD1/PDL1 blocker (BMS-1 (HY-19991)) by thioketal linkage. LTB can further encapsulate photosensitizer chlorine e6 (Ce6) (HY-13594) to construct a co-delivery photodynamic nanoplatform (LTB-6 NPs) by self-assembly [1].
    LTB
  • HY-169436
    Lon-TK

    		PD-1/PD-L1
    Lon-TK is a glycolysis inhibitor + linker conjugate of LTB (HY-169434). LTB is an intelligent responsive prodrug that connects Lonidamine (Lon) (HY-B0486) and a PD-L1 inhibitor (BMS-1, HY-19991) through a thioketal linker. It significantly inhibits the glycolytic metabolism of tumor cells and blocks the PD-1/PD-L1 immune escape pathway. Lon-TK shows potential for application in photodynamic-enhanced immunotherapy research [1].
    Lon-TK

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