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Results for "

Baccatin III

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

4

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6985
    Baccatin III
    1 Publications Verification

    Others Cancer
    Baccatin III is an orally available, selective inhibitor of the TGF-β1 signaling pathway and myeloid-derived suppressor cell (MDSC) activation. Baccatin III targets the AKT/STAT6 and Smad2/3 pathways, blocking TGF-β1-induced fibroblast differentiation and MDSC-mediated immunosuppression. Baccatin III exerts anti-inflammatory and anti-fibrotic effects by inhibiting macrophage activation and extracellular matrix deposition, and shows potential in the treatment of pulmonary fibrosis and cancer in terms of regulating the tumor immune microenvironment[1][2].
    Baccatin III
  • HY-N6985R

    Others Cancer
    Baccatin III (Standard) is the analytical standard of Baccatin III. This product is intended for research and analytical applications. Baccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs .
    Baccatin III (Standard)
  • HY-N8070

    Baccatin III 13-cinnamate

    Others Others
    13-O-Cinnamoylbaccatin III (Baccatin III 13-cinnamate) is a taxane that can be found in the twigs of Taxus mairei .
    13-O-Cinnamoylbaccatin III
  • HY-W777110

    7-O-(Triethylsilyl)Baccatin III

    Drug Intermediate Cancer
    7-(Triethylsilyl)baccatin III (7-O-(Triethylsilyl)baccatin III) is intermediate for preparation of the antitumor agent Paclitaxel (HY-B0015) .
    7-(Triethylsilyl)baccatin III
  • HY-W778546

    Others Cancer
    7-epi-10-Deacetyl baccatin III can be isolated from the degradation impurities in Docetaxel (HY-B0011) .
    7-epi-10-Deacetyl baccatin III
  • HY-W778547

    10-DehydroBaccatin V

    Drug Intermediate Cancer
    7-epi-10-Oxo-10-deacetyl baccatin III (10-Dehydrobaccatin V) can be isolated from the degradation impurities in Docetaxel (HY-B0011) .
    7-epi-10-Oxo-10-deacetyl baccatin III
  • HY-125374A

    XRP9881 dihydrate

    Microtubule/Tubulin Cancer
    Larotaxel (dihydrate) (XRP9881 (dihydrate)), a new taxane compound prepared by partial synthesis from 10-deacetyl baccatin III, is active against tumors .
    Larotaxel dihydrate

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