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Results for "

Bee

" in MedChemExpress (MCE) Product Catalog:

29

Inhibitors & Agonists

8

Peptides

11

Natural
Products

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N1363
    Royal Jelly acid
    4 Publications Verification

    (E)-Queen Bee Acid; (E)-10-Hydroxy-2-decenoic acid

    		 Endogenous Metabolite NO Synthase NF-κB Parasite IFNAR Infection Neurological Disease Inflammation/Immunology Cancer
    Royal Jelly Acid ((E)-Queen Bee Acid) is a major fatty acid found in royal jelly with oral bioavailability, exhibiting anti-inflammatory, anticancer, antimalarial, antiprotozoal, and neuroregulatory activities. Royal Jelly Acid can be used for research in various fields, including cancer, infections, immune inflammation, and neurological diseases .
    Royal Jelly acid
  • HY-128030
    Makisterone A

    		Others Endocrinology
    Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera .
    Makisterone A
  • HY-W587960
    Hercynine

    Histidine-betaine

    		 Drug Metabolite Drug Intermediate Metabolic Disease
    Hercynine (Histidine-betaine) is an intermediate (precursor) and a redox metabolite of Ergothioneine (HY-N1914), which is found in the fine leaf algae, Schizosaccharomyces cerevisiae and honey bees. Hercynine has no effect on scavenging •OH radicals .
    Hercynine
  • HY-W592871
    10-Hydroxy-2-decenoic acid

    10-HDA; Queen Bee Acid

    		 mTOR Cardiovascular Disease Inflammation/Immunology Cancer
    10-Hydroxy-2-decenoic acid (10-HDA) is the major lipid component of royal jelly produced by honeybees. 10-Hydroxy-2-decenoic acid has several health-beneficial effects in mammals, such as antitumor activity, anti-inflammatory activity, and antiangiogenic activity. 10-Hydroxy-2-decenoic acid also extends the lifespan of C. elegans .
    10-Hydroxy-2-decenoic acid
  • HY-N8491A
    (+)-Dihydrocarvone

    		Others Others
    (+)-Dihydrocarvone elicits strong antennal responses of A. mellifera. (+)-Dihydrocarvone influences bee foraging preference for tomato .
    (+)-Dihydrocarvone
  • HY-N0073A
    Spirostan-3-ol

    		Insecticide Others
    Spirostan-3-ol is a useful tool to keep bees away from areas recently treated with toxic insecticides .
    Spirostan-3-ol
  • HY-N1363R
    Royal Jelly acid (Standard)

    (E)-Queen Bee Acid (Standard); (E)-10-Hydroxy-2-decenoic acid (Standard)

    		 Endogenous Metabolite Neurological Disease
    Royal Jelly acid (Standard) is the analytical standard of Royal Jelly acid. This product is intended for research and analytical applications. Royal Jelly acid (Queen Bee Acid) is a fatty acid constituent of royal jelly, promotes the growth and protection of neurons, reduces anxiety-like phenotypes .
    Royal Jelly acid (Standard)
  • HY-P5629
    MCF

    		Bacterial Infection
    MCF is an antimicrobial peptide derived from bee venom. MCF has activity against E.coli W 160-37, S.aureus 8530 and B.subtilis, the MIC values are 35-45 μg/ml, 25-35 μg/ml and 15-25 μg/ml .
    MCF
  • HY-121461
    A25822B

    15-Azasterol

    		 Fungal Infection
    A25822B is an antifungal agent, with a MIC of 1 μM for Ascosphaera apis. A25822B causes conformational changes in mitochondria and disruption of spore membrane structure. A25822B can be used for the research of bee chalk disease .
    A25822B
  • HY-P10596
    Lasioglossin-III

    		Bacterial Fungal Infection Cancer
    Lasioglossin-III is an antimicrobial peptide that can be isolated from the venom of wild bees. Lasioglossin-III has high antibacterial activity against Gram-positive and Gram-negative bacteria, antifungal activity and antitumor activity. Lasioglossin-III has certain cytotoxicity against three cancer cell lines (HeLa S3, CRC SW 480 and CCRF-CEM T) with IC50 values ​​of 4, 18 and 5 μM, respectively .
    Lasioglossin-III
  • HY-13211
    (E)-2-Decenoic acid

    trans-2-Decenoic acid

    		 Endogenous Metabolite Cancer
    (E)-2-Decenoic acid is an interesting fatty acid isolated from royal jelly secretions of honey bees.
    (E)-2-Decenoic acid
  • HY-N9512
    Lycopsamine N-oxide

    		Others Others
    Lycopsamine N-oxide, an N-oxide of Lycopsamine which is a pyrrolizidine alkaloid, can be found in honey and bee pollen .
    Lycopsamine N-oxide
  • HY-133968S1
    24-Methylenecholesterol-13C

    Ostreasterol-13C

    		 Isotope-Labeled Compounds Acyltransferase Others
    24-Methylenecholesterol- 13C (Ostreasterol- 13C) is the 13C labeled 24-Methylenecholesterol (HY-133968) . 24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology .
    24-Methylenecholesterol-13C
  • HY-P1987
    Mast cell degranulating peptide (28-49)

    		Calcium Channel Neurological Disease
    Mast cell degranulating peptide (28-49) is a depolarizing agent from bee venom, it can raise the content of cGMP level in mouse cerebellar slices .
    Mast cell degranulating peptide (28-49)
  • HY-12537
    Peptide 401

    		Histamine Receptor 5-HT Receptor Inflammation/Immunology Endocrinology
    Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT).
    Peptide 401
  • HY-W075032
    Acrinathrin

    		Insecticide Others
    Acrinathrin is a synthetic pyrethroid active ingredient. After experimental treatment for the prevention and control of bee mites, its residues in honey and beeswax are below a certain value, which is more favorable from the perspective of food hygiene.
    Acrinathrin
  • HY-N9512S
    Lycopsamine N-oxide-d3

    		Isotope-Labeled Compounds Others
    Lycopsamine N-oxide-d3 is the deuterium labeled Lycopsamine N-oxide. Lycopsamine N-oxide, an N-oxide of Lycopsamine which is a pyrrolizidine alkaloid, can be found in honey and bee pollen[1].
    Lycopsamine N-oxide-d3
  • HY-125744
    Palmitoyl thio-PC

    		Biochemical Assay Reagents Others
    Palmitoyl thio-PC is a chromogenic substrate specific for PLA2 with a palmitoyl thioester at the sn-2 position. Palmitoyl thio-PC could be used to measure bee-venom sPLA2 activity in a phospholipid system .
    Palmitoyl thio-PC
  • HY-P0256
    Apamin
    5 Publications Verification

    Apamine

    		 Potassium Channel Neurological Disease Inflammation/Immunology
    Apamin (Apamine) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca 2+-activated K + (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity .
    Apamin
  • HY-P0256A
    Apamin TFA
    5 Publications Verification

    Apamine TFA

    		 Potassium Channel Neurological Disease Inflammation/Immunology
    Apamin TFA (Apamine TFA) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca 2+-activated K + (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity .
    Apamin TFA
  • HY-P3914
    Cecropin A (1-7)-Melittin A (2-9)

    Oct-CA(1-7)M(2-9)

    		 Bacterial Infection
    Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides .
    Cecropin A (1-7)-Melittin A (2-9)
  • HY-13211R
    (E)-2-Decenoic acid (Standard)

    trans-2-Decenoic acid (Standard)

    		 Endogenous Metabolite Cancer
    (E)-2-Decenoic acid (Standard) is the analytical standard of (E)-2-Decenoic acid. This product is intended for research and analytical applications. (E)-2-Decenoic acid is an interesting fatty acid isolated from royal jelly secretions of honey bees.
    (E)-2-Decenoic acid (Standard)
  • HY-N2927
    Costic acid

    β-Costic acid

    		 Parasite Infection
    Costic acid (β-Costic acid) is a natural product, that can be isolated from Dittrichia viscosa. Costic acid exhibits potent in vivo acaricidal activity against the parasite. Costic acid is not toxic for human umbilical vein endothelial cells (HUVEC) at concentrations of up to 230 μM. Costic acid can be used for the research of varroosis in honey bee colonies .
    Costic acid
  • HY-P10547
    Macropin

    MAC-1 peptide

    		 Bacterial Infection
    Macropin (MAC-1 peptide) is an antimicrobial peptide found in the venom of the solitary bee Macropis fulvipes. Macropin has antibacterial activity against both Gram-positive and Gram-negative bacteria, and also exhibits inhibitory activity against fungi and moderate hemolytic activity against human erythrocytes. Macropin can be used in research on anti-infective therapy .
    Macropin
  • HY-103474
    Bicuculline methiodide
    Maximum Cited Publications
    26 Publications Verification

    (-)-Bicuculline methiodide; l-Bicuculline methiodide

    		 GABA Receptor Neurological Disease
    Bicuculline methiodide is a potent GABA(A) receptors blocker. Bicuculline methiodide alters membrane properties and firing pattern. Bicuculline methiodide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca 2+ -activated K + channels. Bicuculline methiodide facilitates burst firing via blocking apamin-sensitive Ca 2+ -activated K + current .
    Bicuculline methiodide
  • HY-133968
    24-Methylenecholesterol

    Ostreasterol

    		 Acyltransferase Inflammation/Immunology
    24-Methylenecholesterol is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth .
    24-Methylenecholesterol
  • HY-133968R
    24-Methylenecholesterol (Standard)

    Ostreasterol (Standard)

    		 Acyltransferase Inflammation/Immunology
    24-Methylenecholesterol (Standard) is the analytical standard of 24-Methylenecholesterol. This product is intended for research and analytical applications. 24-Methylenecholesterol is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth[1][2][3].
    24-Methylenecholesterol (Standard)
  • HY-145295R
    Flupyradifurone (Standard)

    		nAChR Infection
    Flupyradifurone (Standard) is the analytical standard of Flupyradifurone. This product is intended for research and analytical applications. Flupyradifurone is a systemic nAChR agonist that interferes with signal transduction in the central nervous system of sucking pests. Flupyradifurone can be used as a butenolide insecticide .
    Flupyradifurone (Standard)
  • HY-145295
    Flupyradifurone

    		nAChR Infection
    Flupyradifurone is a systemic nAChR agonist that interferes with signal transduction in the central nervous system of sucking pests. Flupyradifurone can be used as a butenolide insecticide .
    Flupyradifurone

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