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CB2 receptor antagonist 1

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Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116637
    Tetrahydromagnolol

    Magnolignan

    		 Cannabinoid Receptor GPR55 Inflammation/Immunology
    Tetrahydromagnolol (Magnolignan), a main metabolite of Magnolol, is a potent and selective cannabinoid CB2 receptor agonist with an EC50 of 170 nM and a Ki of 416 nM. Tetrahydromagnolol possesses 20-fold more selective for CB2 receptor than CB1 receptor. Tetrahydromagnolol is also a weak GPR55 receptor antagonist .
    Tetrahydromagnolol
  • HY-147707
    CB2 receptor antagonist 1

    		Cannabinoid Receptor Others
    Hexyl resorcinol derivative 29 has been proved to be a CB2 selective competitive antagonist / reverse agonist with good potency. Olivanol and 5- (2-methyloctane-2-yl) resorcinol derivatives 23 and 24 showed significant antinociceptive activity. Compound 24 was shown to activate cannabinoid and TRPV1 receptors.
    CB2 receptor antagonist 1

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