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CNG

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-137016A
    8-Pcpt-cGMP sodium

    		HCN Channel Neurological Disease
    8-Pcpt-cGMP sodium is the sodium salt form of 8-Pcpt-cGMP (HY-137016). 8-Pcpt-cGMP sodium is an agonist for cyclic nucleotide-gated (CNG) channel with an EC50 of 0.5 μM. 8-Pcpt-cGMP sodium exhibits good membrane permeability. 8-Pcpt-cGMP sodium can be used in studies about the function of CNG channels in visual signal transduction and olfactory transduction .
    8-Pcpt-cGMP sodium
  • HY-137016
    8-Pcpt-cGMP

    		HCN Channel Neurological Disease
    8-Pcpt-cGMP is an agonist for cyclic nucleotide-gated (CNG) channel with an EC50 of 0.5 μM. 8-Pcpt-cGMP exhibits good membrane permeability. 8-Pcpt-cGMP can be used in studies about the function of CNG channels in visual signal transduction and olfactory transduction .
    8-Pcpt-cGMP
  • HY-137108
    Sp-8-pCPT-cGMPS

    		PKA PKG Neurological Disease
    Sp-8-pCPT-cGMPS is a potent cyclic guanosine monophosphate-gated channel agonist and a lipophilic activator of protein kinase G (types I α, I β, and II) and protein kinase A type II with excellent cell membrane permeability and phosphodiesterase stability. Sp-8-pCPT-cGMPS can be used to study the role of cGMP in neural plasticity and synaptic transmission .
    Sp-8-pCPT-cGMPS
  • HY-110221
    Rp-8-pCPT-cGMPS sodium

    		PKG Neurological Disease
    Rp-8-pCPT-cGMPS sodium is the sodium salt form of Rp-8-pCPT-cGMPS. Rp-8-pCPT-cGMPS is an inhibitor for cGMP-dependent protein kinase (cGK). Rp-8-pCPT-cGMPS sodium is an agonist for cyclic nucleotide-gated (CNG) channels in a voltage-dependent manner .
    Rp-8-pCPT-cGMPS sodium
  • HY-137639
    Sp-8-Br-cGMPS

    		HCN Channel Neurological Disease
    Sp-8-Br-cGMPS is an analog of cGMP. Sp-8-Br-cGMPS is an agonist for cGMP-gated cation channels (CNG channels), with an EC50 of 106.5 μM. Sp-8-Br-cGMPS induces the currents, without the ability to stabilize the channel open state as a full agonist .
    Sp-8-Br-cGMPS
  • HY-135110
    Rp-8-Br-cGMPS sodium

    Rp-8-bromo-Cyclic GMPS sodium

    		 Calcium Channel PKG HCN Channel Metabolic Disease
    Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is a potent Ca 2+-ATPase activator. Rp-8-Br-cGMPS is also an agonist of the rod CNG channel and an inhibitor of PKG. Rp-8-Br-cGMPS sodium salt mediates cytosolic Ca 2+ reduction by activating Ca 2+-ATPase and subsequently removing Ca 2+ from the cell .
    Rp-8-Br-cGMPS sodium
  • HY-135110A
    Rp-8-Br-cGMPS

    Rp-8-bromo-Cyclic GMPS

    		 Calcium Channel PKG HCN Channel Metabolic Disease
    Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is a potent Ca 2+-ATPase activator. Rp-8-Br-cGMPS is also an agonist of the rod CNG channel and an inhibitor of PKG. Rp-8-Br-cGMPS sodium salt mediates cytosolic Ca 2+ reduction by activating Ca 2+-ATPase and subsequently removing Ca 2+ from the cell .
    Rp-8-Br-cGMPS

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