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COX-1/2-IN-3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147693
    COX-1/2-IN-3

    		COX Inflammation/Immunology
    COX-1/2-IN-3 (Compound 7a) is a COX-1 and COX-2 inhibitor. COX-2-IN-15 shows anti-inflammatory activity with low toxicity .
    COX-1/2-IN-3
  • HY-169858
    Prostaglandin E2 Inhibitor 3

    		PGE synthase Inflammation/Immunology
    Prostaglandin E2 Inhibitor 3 (Compound 3) is a selectivity microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor (IC50 = 0.2 µM). Prostaglandin E2 Inhibitor 3 has higher selectivity for mPGES-1 than cyclooxygenases (COX)-1/2, 5-lipoxygenase (5-LO), and soluble epoxide hydrolase (sEH). Prostaglandin E2 Inhibitor 3 has anti-inflammatory activity and can attenuate zymosan-induced peritoneal leukocyte migration in mice .
    Prostaglandin E2 Inhibitor 3

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