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Results for "

CRBN ligand-12

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-148290
    KTX-951

    		PROTACs IRAK Cancer
    KTX-951 is an orally active IRAK4 and IMiD (Ikaros/Aiolos) substrates PROTAC degrader. KTX-951 has DC50 of 13 nM, 14 nM and 13 nM for IRAK4, Ikaros and Aiolos, respectively. TX-951 has antitumor activity.(Pink: IRAK4 ligand-12 (HY-48932); Black: Linker (HY-W382009); Blue: CRBN Ligand Pomalidomide (HY-10984))
    KTX-951
  • HY-170058
    CRBN ligand-12

    		Ligands for E3 Ligase E1/E2/E3 Enzyme Cancer
    CRBN ligand-12 (Compound 9) is a CRBN-type E3 ubiquitin ligase ligand. CRBN ligand-12 can be used to prepare PROTACs .
    CRBN ligand-12

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