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CTM

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-A0110A
    Cefotiam hexetil hydrochloride

    CTM-HE hydrochloride; SCE-2174 hydrochloride

    		 Bacterial Antibiotic Infection
    Cefotiam hexetil hydrochloride (CTM-HE) is an oral third-generation cephalosporin, which is a proagent of cefotiam, but has no anti-bacterial property. Cefotiam is an antibiotic .
    Cefotiam hexetil hydrochloride
  • HY-153321
    NX-5948

    BTK-IN-24

    		 Btk PROTACs Inflammation/Immunology Cancer
    NX-5948 (BTK-IN-24) is an orally active chimeric targeting molecule (CTM) that induces specific BTK protein degradation by the cereblon E3 ligase (CRBN) complex without degradation of other cereblon neo-substrates. NX-5948 mediates potent anti-inflammatory activity via BTK degradation with resultant inhibition of B cell activation. NX-5948 exhibits potent tumor growth inhibition in TMD8 xenograft models that contain either wild-type BTK or BTKi-resistant mutations. NX-5948 is efficacious in a mouse collageninduced arthritis (CIA) model. NX-5948 can cross the blood brain barrier (BBB). NX-5948 is a PROTAC composed of the ligand for target protein, a linker, and a cereblon E3 ligase (CRBN) complex (Red: ligand for target protein; Blue: CRBN; Black: linker) .
    NX-5948
  • HY-A0110AR
    Cefotiam hexetil hydrochloride (Standard)

    CTM-HE hydrochloride (Standard); SCE-2174 hydrochloride (Standard)

    		 Bacterial Antibiotic Infection
    Cefotiam hexetil (hydrochloride) (Standard) is the analytical standard of Cefotiam hexetil (hydrochloride). This product is intended for research and analytical applications. Cefotiam hexetil hydrochloride (CTM-HE) is an oral third-generation cephalosporin, which is a proagent of cefotiam, but has no anti-bacterial property. Cefotiam is an antibiotic[1].
    Cefotiam hexetil hydrochloride (Standard)

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