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Results for "

CYP1A Inhibitor

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

2

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0125
    Diosmetin
    5+ Cited Publications

    		 Cytochrome P450 Cancer
    Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity with an IC50 of 40 μM in HepG2 cell.
    Diosmetin
  • HY-B0973
    Dibenzothiophene

    DBT; Diphenylene sulfide

    		 Cytochrome P450 Aryl Hydrocarbon Receptor Metabolic Disease
    Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with Km of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone (HY-114740). Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms .
    Dibenzothiophene
  • HY-121213
    Erysolin

    		Cytochrome P450 Cancer
    Erysolin is a CYP1A inhibitor with antigenic toxicity. Erysolin reduces benzo(a)pyrene-induced genotoxicity .
    Erysolin
  • HY-B0973R
    Dibenzothiophene (Standard)

    DBT (Standard); Diphenylene sulfide (Standard)

    		 Drug Intermediate Others
    Dibenzothiophene (Standard) is the analytical standard of Dibenzothiophene. This product is intended for research and analytical applications. Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with Km of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone (HY-114740). Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms .
    Dibenzothiophene (Standard)
  • HY-118216
    Bitertanol

    Biloxazol

    		 Fungal Cytochrome P450 Infection
    Bitertanol (Biloxazol) is a potent antifungal agent. Bitertanol also is an CYP1A1, CYP2B, and CYP3A inducer in vivo and an CYP1A inhibitor in vitro .
    Bitertanol
  • HY-N0125S
    Diosmetin-d3

    		Isotope-Labeled Compounds Cytochrome P450 Cancer
    Diosmetin-d3 is the deuterium labeled Diosmetin. Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity with an IC50 of 40 μM in HepG2 cell.
    Diosmetin-d3
  • HY-N0125R
    Diosmetin (Standard)

    		Cytochrome P450 Cancer
    Diosmetin (Standard) is the analytical standard of Diosmetin. This product is intended for research and analytical applications. Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity with an IC50 of 40 μM in HepG2 cell.
    Diosmetin (Standard)
  • HY-W401407
    Diosmetin-3-O-glucuronide

    		Drug Metabolite Cytochrome P450 Metabolic Disease
    Diosmetin-3-O-glucuronide is a major circulating metabolite of Diosmetin (HY-N0125) in plasma and in urine. Diosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity .
    Diosmetin-3-O-glucuronide
  • HY-118216R
    Bitertanol (Standard)

    		Fungal Cytochrome P450 Infection
    Bitertanol (Standard) is the analytical standard of Bitertanol. This product is intended for research and analytical applications. Bitertanol (Biloxazol) is a potent antifungal agent. Bitertanol also is an CYP1A1, CYP2B, and CYP3A inducer in vivo and an CYP1A inhibitor in vitro .
    Bitertanol (Standard)
  • HY-120377
    CYP1A1 inhibitor 8a

    		HBV Cancer
    CYP1A1 inhibitor 8a is a compound that potently and selectively inhibits the CYP1A1 enzyme and has the potential to prevent cancer. CYP1A1 inhibitor 8a exhibits more than 10-fold selectivity for CYP1A1 and more than 100-fold selectivity over other enzymes in the CYP1 subfamily. CYP1A1 inhibitor 8a can effectively antagonize B[a]P-mediated activation of the aryl hydrocarbon receptor (AhR) in yeast cells and protect human cells from CYP1A1-mediated B[a]P toxicity. CYP1A1 inhibitor 8a has the potential to be developed as a cancer chemopreventive agent .
    CYP1A1 inhibitor 8a

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