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Results for "

CYP4A3

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-124527
    HET0016
    2 Publications Verification

    		 Cytochrome P450 Cardiovascular Disease Cancer
    HET0016 is a potent and selective 20-hydroxyeicosatetraenoic acid (20-HETE) synthase inhibitor, with IC50 values of 17.7 nM, 12.1 nM and 20.6 nM for recombinant CYP4A1-, CYP4A2- and CYP4A3-catalyzed 20-HETE synthesis, respectively. HET0016 also is a selective CYP450 inhibitor, which has been shown to inhibit angiogenesis and tumor growth .
    HET0016
  • HY-119647
    PPOH

    		COX Cytochrome P450 Others
    PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC50 values of 22 μM and 6.5 μM, respectively . PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    PPOH
  • HY-E70499
    Human CYP4F3,High-Reductase

    		Cytochrome P450 Metabolic Disease
    Human CYP4F3, High-Reductase, a recombinant CYP4F3, is a member of the CYP enzyme family. CYP4F3 is an enzyme mainly expressed in polymorphonuclear leukocytes .
    Human CYP4F3,High-Reductase
  • HY-E70498
    Human CYP4F3,Low-Reductase

    		Cytochrome P450 Metabolic Disease
    Human CYP4F3, Low-Reductase, a recombinant CYP4F3, is a member of the CYP enzyme family. CYP4F3 is an enzyme mainly expressed in polymorphonuclear leukocytes .
    Human CYP4F3,Low-Reductase
  • HY-E70501
    Human CYP4F3,High-Reductase+b5

    		Cytochrome P450 Metabolic Disease
    Human CYP4F3, High-Reductase+b5, a recombinant CYP4F3, is a member of the CYP enzyme family. CYP4F3 is an enzyme mainly expressed in polymorphonuclear leukocytes .
    Human CYP4F3,High-Reductase+b5
  • HY-E70500
    Human CYP4F3,Low-Reductase+b5

    		Cytochrome P450 Metabolic Disease
    Human CYP4F3, Low-Reductase+b5, a recombinant CYP4F3, is a member of the CYP enzyme family. CYP4F3 is an enzyme mainly expressed in polymorphonuclear leukocytes .
    Human CYP4F3,Low-Reductase+b5
  • HY-RS03482
    CYP4F3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CYP4F3 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP4F3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CYP4F3 Human Pre-designed siRNA Set A
    CYP4F3 Human Pre-designed siRNA Set A
  • HY-113777
    22-HDHA

    22-Hydroxy Docosahexaenoic acid; 22-OH DHA

    		 Cytochrome P450 Metabolic Disease
    22-HDHA (22-Hydroxy Docosahexaenoic acid) is an oxidation product of docosahexaenoic acid. In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes. Serum levels of 22-HDHA increase following dietary DHA supplementation in humans.
    22-HDHA
  • HY-121888
    20-HEPE

    		PPAR Metabolic Disease
    20-HEPE is a metabolite of eicosapentaenoic acid formed by ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B. At 10 μM, it activates peroxisome proliferator-activated receptor α (PPARα) in COS-7 cells expressing a luciferase reporter gene. 20-HEPE also activates mouse transient receptor potential vanilloid receptor 1 (mTRPV1) in vitro but lacks analgesic activity in rats.
    20-HEPE

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