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Results for "

Colon contraction

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139119
    Prostaglandin F2α dimethyl amide

    		Prostaglandin Receptor Others
    Prostaglandin F2α dimethyl amide is an antagonist for Prostaglandin F2α (HY-12956), which blocks 50% contraction on gerbilMeriones unguiculatus colon induced by PGF2α at 3.2 μg/mL .
    Prostaglandin F2α dimethyl amide
  • HY-112707
    AM9405

    		Cannabinoid Receptor 5-HT Receptor Neurological Disease
    AM9405 is a novel peripherally active cannabinoid type 1 (CB1) and serotonin type 3 receptor agonist. AM9405 inhibits twitch contraction of the ileum and the colon with IC50s of 45.71 and 0.076 nM, respectively.
    AM9405
  • HY-106323
    [Leu13]-Motilin

    KW-5139

    		 Motilin Receptor Metabolic Disease
    [Leu13]-Motilin (KW-5139) is a motilin analogue. [Leu13]-Motilin stimulates gastrointestinal motility in the rabbit. [Leu13]-Motilin causes concentration-dependent contractions of the gastric antrum, duodenum, jejunum, ileum and the descending colon in vitro .
    [Leu13]-Motilin
  • HY-167902
    YM-31636 free base

    		5-HT Receptor Metabolic Disease
    YM-31636 free base is an orally active, potent and selective 5-HT3 receptor agonist with a Ki value of 0.2 nM. YM-31636 free base induces contraction of isolated guinea pig distal colon. YM-31636 free base induces tachycardia with the relative intrinsic activity of approximately 0.23 in isolated guinea pig right atrium. YM-31636 free base is promising for research of constipation .
    YM-31636 free base
  • HY-101303
    5-MCA-NAT

    		Melatonin Receptor Others
    5-MCA-NAT is a melatonin agonist that may target the melatoninMT3 receptor. 5-MCA-NAT can contract the colonic band in a concentration-dependent manner and reduce intraocular pressure (IOP) in glaucomatous monkey eyes, inhibiting the increase in IOP .
    5-MCA-NAT

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