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DA-143

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-169121
    DA-143

    		mTOR PI3K Cancer
    DA-143 is a selective DNA-PKcs inhibitor (IC50: 2.5 nM), and the IC50s for mTOR, PI3KΔ, and ATM are 280 nM, 106 nM and 6,594 nM respectively. DA-143 blocks phosphorylation of DNA-PKcs substrates. DA-143 sensitizes cancer cells to Doxorubicin (HY-15142) .
    DA-143

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