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DPP-4-IN-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Dipeptidyl Peptidase (6) Amylases (1) Glycosidase (1) Histone Methyltransferase (1) Interleukin Related (1) NOD-like Receptor (NLR) (1) Phosphatase (1) SARS-CoV (1) TNF Receptor (1)
By Research Areas:	Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (1) Metabolic Disease (6)

9

Inhibitors & Agonists

1

Inhibitory Antibodies

1

Isotope-Labeled Compounds

Targets Recommended: Dipeptidyl Peptidase Dan family AIM2 NEKs

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Sitagliptin fenilalanil	Dipeptidyl Peptidase	Metabolic Disease
Sitagliptin fenilalanil is a dipeptidyl aminopeptidase 4 (DPP-4) inhibitor .

Sitagliptin fenilalanil hydrochloride	Dipeptidyl Peptidase	Metabolic Disease
Sitagliptin fenilalanil hydrochloride is a dipeptidyl aminopeptidase 4 (DPP-4) inhibitor .

*DPP-4-IN-1*	Dipeptidyl Peptidase	Metabolic Disease
DPP-4-IN-1 (compound d1) is a potent DPP-4 (dipeptidyl peptidase 4) inhibitor, with an IC₅₀of 49 nM. DPP-4-IN-1 is a structurally analogs of Alogliptin (HY-A0023A). DPP-4-IN-1 can be used for diabetes research .

ZINC000003015356	Dipeptidyl Peptidase	Metabolic Disease
ZINC000003015356 is a *DPP4* inhibitor .

DPP4-In hydrochloride	Interleukin Related TNF Receptor NOD-like Receptor (NLR)	Inflammation/Immunology
DPP4-In (hydrochloride) is an inhibitor of dipeptidyl peptidase 4 (DPP4) that can reduce DPP4 expression .

Teneligliptin-d8 MP-513 d₈	Dipeptidyl Peptidase	Cardiovascular Disease
Teneligliptin-d₈ is a deuterium labeled Teneligliptin (MP-513). Teneligliptin is a potent, orally available, competitive, and long-lasting DPP-4 inhibitor[1].

Anti-MERS-3A1 mAb MERS-3A1; MERS Antibody-3A1	SARS-CoV	Infection
Anti-MERS-3A1 mAb (MERS-3A1) is a human monoclonal IgG1 antibody with the high binding affinity produced in CHO cells. Anti-MERS-3A1 mAb bocks the binding of MERS-CoV spike protein to DPP4 receptor .

Antidiabetic agent 2	Dipeptidyl Peptidase Phosphatase Amylases Glycosidase	Metabolic Disease
Antidiabetic agent 2 (Compound 56) is a glucose-uptake promoter. Antidiabetic agent 2 inhibits *DPP-4, PTP-1B*, α-amylase, and α-glucosidase with IC₅₀s of 0.036, 0.042, 0.241, 0.185 μM. Antidiabetic agent 2 decreases blood glucose levels .

Bisegliptin KRP-104	Histone Methyltransferase	Metabolic Disease
Bisegliptin (KRP-104) is a small molecule compound with antidiabetic activity. Bisegliptin is metabolized mainly by converting the cyano group to the carboxylic acid form, and DPP-4 plays a partial role in its metabolism. The carboxylic acid metabolite of bisegliptin can be detected both in vivo and in vitro. In rat experiments, the plasma concentration of the carboxylic acid metabolite of bisegliptin was affected by other DPP inhibitors, showing the complexity of its metabolic process. The amide intermediate of bisegliptin was detected both in vivo and in vitro, and its conversion rate was significantly faster than that of the parent compound when incubated with DPP-4 .

Cat. No.	Product Name	Target	Research Area

Anti-MERS-3A1 mAb MERS-3A1; MERS Antibody-3A1	SARS-CoV	Infection
Anti-MERS-3A1 mAb (MERS-3A1) is a human monoclonal IgG1 antibody with the high binding affinity produced in CHO cells. Anti-MERS-3A1 mAb bocks the binding of MERS-CoV spike protein to DPP4 receptor .

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