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Results for "

Dermatitis

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (3) Adrenergic Receptor (3) Akt (1) Amino Acid Derivatives (2) Angiotensin Receptor (1) Antibiotic (8) AP-1 (1) Apoptosis (5) Aryl Hydrocarbon Receptor (1) Autophagy (4) Bacterial (10) Biochemical Assay Reagents (1) CCR (1) CD28 (1) CD3 (1) COX (2) CXCR (1) Cytochrome P450 (2) Dopamine Receptor (3) Drug Metabolite (3) Endogenous Metabolite (2) ERK (1) FGFR (1) Filovirus (1) Fluorescent Dye (1) Fungal (1) Glucocorticoid Receptor (10) Histamine Receptor (9) HIV (1) Interleukin Related (11) Isotope-Labeled Compounds (1) JAK (3) Mitochondrial Metabolism (1) MMP (2) mTOR (1) Neurokinin Receptor (1) NF-κB (3) NO Synthase (1) NOD-like Receptor (NLR) (1) Nuclear Factor of activated T Cells (NFAT) (1) Opioid Receptor (1) Parasite (6) PD-1/PD-L1 (1) Phosphatase (2) Phosphodiesterase (PDE) (7) PI3K (2) Prostaglandin Receptor (1) Reactive Oxygen Species (4) ROR (1) Syk (2) Toll-like Receptor (TLR) (1) TRP Channel (1) Virus Protease (1)
By Research Areas:	Cancer (16) Endocrinology (11) Infection (16) Inflammation/Immunology (76) Metabolic Disease (1) Neurological Disease (9)

By Targets:

5-HT Receptor (3)

Adrenergic Receptor (3)

Akt (1)

Amino Acid Derivatives (2)

Angiotensin Receptor (1)

Antibiotic (8)

AP-1 (1)

Apoptosis (5)

Aryl Hydrocarbon Receptor (1)

Autophagy (4)

Bacterial (10)

Biochemical Assay Reagents (1)

CCR (1)

CD28 (1)

CD3 (1)

COX (2)

CXCR (1)

Cytochrome P450 (2)

Dopamine Receptor (3)

Drug Metabolite (3)

Endogenous Metabolite (2)

ERK (1)

FGFR (1)

Filovirus (1)

Fluorescent Dye (1)

Fungal (1)

Glucocorticoid Receptor (10)

Histamine Receptor (9)

HIV (1)

Interleukin Related (11)

Isotope-Labeled Compounds (1)

JAK (3)

Mitochondrial Metabolism (1)

MMP (2)

mTOR (1)

Neurokinin Receptor (1)

NF-κB (3)

NO Synthase (1)

NOD-like Receptor (NLR) (1)

Nuclear Factor of activated T Cells (NFAT) (1)

Opioid Receptor (1)

Parasite (6)

PD-1/PD-L1 (1)

Phosphatase (2)

Phosphodiesterase (PDE) (7)

PI3K (2)

Prostaglandin Receptor (1)

Reactive Oxygen Species (4)

ROR (1)

Syk (2)

Toll-like Receptor (TLR) (1)

TRP Channel (1)

Virus Protease (1)

By Research Areas:

Cancer (16)

Endocrinology (11)

Infection (16)

Inflammation/Immunology (76)

Metabolic Disease (1)

Neurological Disease (9)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100009

Ufenamate Flufenamic acid butyl ester; Butyl flufenamate	COX Prostaglandin Receptor	Inflammation/Immunology
Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory drug that can be used in the study of skin diseases such as acute and chronic eczema, contact dermatitis, diaper dermatitis, miliary rashes and atopic dermatitis. Ufenamate has a certain photoprotective effect, reduces the degree of skin erythema and swelling in the photoaging model, downregulates the expression level of COX-2 and can promote the healing of mouse skull defects by secreting BMP2 .

HY-145551

Atinvicitinib	Others	Inflammation/Immunology
Atinvicitinib is a kind of pyrazole compound. Atinvicitinib has the potential for the research of atopic dermatitis (extracted from patent WO2021123094A1) .

HY-N0508

Rosin 1 Publications Verification	Others	Inflammation/Immunology
Rosin is isolated from pine wood or pine stumps, Rosin is a frequent contact allergen which induces allergic contact dermatitis .

HY-P99301

Lokivetmab Anti-Canine IL31 Recombinant Antibody	Interleukin Related	Inflammation/Immunology
Lokivetmab (Anti-Canine IL31 Recombinant Antibody) is an anti-canine IL-31 monoclonal antibody that can be used for the research of atopic dermatitis (AD) in dogs .

HY-B1365

Prednicarbate	Glucocorticoid Receptor	Inflammation/Immunology
Prednicarbate is a topical corticosteroid agent. Prednicarbate can be used for the research of inflammatory skin diseases, such as atopic dermatitis .

HY-A0150

Alclometasone 7a-Chloro-16a-methyl prednisolone	Glucocorticoid Receptor	Inflammation/Immunology Cancer
Alclometasone (7a-Chloro-16a-methyl prednisolone) is a glucocorticoid and inhibits the release of pro-inflammatory mediators from leukocytes. Alclometasone can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis, eczema, psoriasis and allergic dermatitis .

HY-12348

LEO 29102	Phosphodiesterase (PDE)	Inflammation/Immunology
LEO 29102 is a potent phosphodiesterase 4 (PDE4) inhibitor with an IC₅₀ value of 5 nM. LEO 29102 inhibits TNFα release. LEO 29102 has the potential for the research of atopic dermatitis .

HY-16473

Sulfoxone disodium Aldesulfone disodium	Antibiotic Bacterial	Infection Inflammation/Immunology
Sulfoxone (Aldesulfone) disodium is an orally active sulphonamide antibiotic that is used against leprosy. Sulfoxone disodium can also be used in study of dermatitis herpetiformis .

HY-159514

Graveolide	NO Synthase COX	Inflammation/Immunology
Graveolide (Compound 5) is a sesquiterpenoid compound that can be isolated from C. abrotanoides. Graveolide possesses anti-inflammatory activity and can be utilized in the research of atopic dermatitis .

HY-N0508R

Rosin (Standard)	Others	Inflammation/Immunology
Rosin (Standard) is the analytical standard of Rosin. This product is intended for research and analytical applications. Rosin is isolated from pine wood or pine stumps, Rosin is a frequent contact allergen which induces allergic contact dermatitis .

HY-B1365R

Prednicarbate (Standard)	Glucocorticoid Receptor	Inflammation/Immunology
Prednicarbate (Standard) is the analytical standard of Prednicarbate. This product is intended for research and analytical applications. Prednicarbate is a topical corticosteroid agent. Prednicarbate can be used for the research of inflammatory skin diseases, such as atopic dermatitis .

HY-131707

LEO 39652	Phosphodiesterase (PDE)	Inflammation/Immunology
LEO 39652 is a dual-soft PDE4 inhibitor with IC₅₀s of 1.2 nM, 1.2 nM, 3.0 nM and 3.8 nM for PDE4A, PDE4B, PDE4C and PDE4D, respectively. LEO 39652 also inhibits TNF-α with an IC₅₀ value of 6.0 nM. LEO 39652 is used for topical research of Atopic dermatitis (AD) .

HY-151876

Glucocorticoid receptor modulator 1	Glucocorticoid Receptor NF-κB AP-1	Inflammation/Immunology
Glucocorticoid receptor modulator 1 is a highly potent and orally active non-steroidal selective glucocorticoid receptor modulator with an IC₅₀ value of 9 nM and 130 nM for NF-κB and AP-1, respectively. Glucocorticoid receptor modulator 1 can effectively reduce the expression of inflammatory factors IL-6, IL-1β, TNF-α, also can relieve dermatitis in mice .

HY-168033

AhR agonist 8	Aryl Hydrocarbon Receptor	Inflammation/Immunology
AhR agonist 8 (compound 9) is a potent Aryl Hydrocarbon Receptor (AhR) agonist with an EC₅₀ of 0.154 nM. AhR agonist 8 can be used in the study of psoriasis and atopic dermatitis .

HY-P99053

Tralokinumab	Interleukin Related	Inflammation/Immunology
Tralokinumab, a fully human IgG4 monoclonal antibody, specifically binds with high affinity to IL-13 alone, preventing its interaction with the receptor and subsequent downstream signalling. Tralokinumab can be used for the research of the atopic dermatitis (AD) .

HY-144683

PF-07038124	Phosphodiesterase (PDE)	Inflammation/Immunology
PF-07038124 is a PDE4 inhibitor with an IC₅₀ of 0.5 nM for PDE4B2. PF-07038124 shows inhibitory activities against IL-13, IL4, and IFNγ (IC₅₀=125, 4.1, 1.06 nM, respectively). PF-07038124 can be used for research of atopic dermatitis and plaque psoriasis .

HY-144683A

PF-07038124 hydrochloride	Phosphodiesterase (PDE)	Inflammation/Immunology
PF-07038124 hydrochloride is a PDE4 inhibitor with an IC₅₀ of 0.5 nM for PDE4B2. PF-07038124 hydrochloride shows inhibitory activities against IL-13, IL4, and IFNγ (IC₅₀=125, 4.1, 1.06 nM, respectively). PF-07038124 hydrochloride can be used for research of atopic dermatitis and plaque psoriasis .

HY-B1616

Clobetasone butyrate 1 Publications Verification	Glucocorticoid Receptor	Inflammation/Immunology
Clobetasone butyrate is a synthetic glucocorticoid and has topical anti-inflammatory activity especially in skin. Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic?dermatitis and psoriasis .

HY-148074

Zelnecirnon RPT193	CCR	Inflammation/Immunology
Zelnecirnon (RPT193) is an orally active inhibitor of CCR4, blocks the recruitment of Th2 inflammatory immune cells into inflamed tissues. Zelnecirnon can be used for allergic inflammation in atopic dermatitis, asthma, and other diseases research .

HY-P99162

Nemolizumab CIM331	Interleukin Related	Inflammation/Immunology
Nemolizumab (CIM331) is a humanized monoclonal antibody that targets the human interleukin-31 receptor a, preventing interleukin-31 (IL-31) from binding to its receptor and the subsequent signaling. Nemolizumab can help reduce itching and sleep disturbances, and it is being studied for atopic dermatitis (AD) .

HY-109085

Difamilast 2 Publications Verification OPA-15406	Phosphodiesterase (PDE)	Inflammation/Immunology
Difamilast (OPA-15406) is a topical, selective and nonsteroidal phosphodiesterase-4 (PDE4) inhibitor with particularly efficient inhibition of subtype B (IC₅₀=11.2 nM). Difamilast can be used for the research of mild to moderate atopic dermatitis (AD) .

HY-153565

Immune cell migration-IN-1	Others	Inflammation/Immunology
Immune cell migration-IN-1 (compound 2) is a potent agent to inhibit immune cell migration. Immune cell migration-IN-1 can be used for research in alleviating dry eye diseases, eczema dermatitis and psoriasis .

HY-P1722

Spantide II	Neurokinin Receptor	Inflammation/Immunology
Spantide II, an undecapeptide substance P (SP) analog, is a potent neurokinin-1 receptor (NK-1R) antagonist. Spantide II binds with NK-1R and blocks proinflammatory activities associated with SP. Spantide II can be used in the research of inflammatory skin disorders, such as psoriasis and contact dermatitis .

HY-W010520

Methylisothiazolinone	Bacterial MMP Apoptosis Fungal	Infection Inflammation/Immunology
Methylothiazolinone is a bacterial and fungal inhibitor and preservative, as well as a sensitizer. Methylisothiazolinone can activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells to induce apoptosis and inflammatory response. Methylisothiazolinone can promote the development of atopic dermatitis in mice by disrupting Th2/Th17 related immune responses. Methylisothiazolinone can cause mitochondrial damage in the endothelium of rat cerebral blood vessels .

HY-W010520R

Methylisothiazolinone (Standard)	Bacterial MMP	Infection Inflammation/Immunology
Methylisothiazolinone (Standard) is the analytical standard of Methylisothiazolinone. Methylothiazolinone is a fungicide and preservative, as well as a sensitizer. Methylisothiazolinone can activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells to induce cell apoptosis and inflammatory response. Methylisothiazolinone can promote the development of atopic dermatitis in mice by disrupting Th2/Th17 related immune responses. Methylisothiazolinone can cause mitochondrial damage in the endothelium of rat cerebral blood vessels .

HY-109085R

Difamilast (Standard)	Phosphodiesterase (PDE)	Inflammation/Immunology
Difamilast (Standard) is the analytical standard of Difamilast. This product is intended for research and analytical applications. Difamilast (OPA-15406) is a topical, selective and nonsteroidal phosphodiesterase-4 (PDE4) inhibitor with particularly efficient inhibition of subtype B (IC₅₀=11.2 nM). Difamilast can be used for the research of mild to moderate atopic dermatitis (AD) .

HY-P99519

Vixarelimab 1 Publications Verification KPL-716	Interleukin Related	Inflammation/Immunology
Vixarelimab (KPL-716) is a human anti-oncostatin M (OSM) monoclonal antibody that binds to the beta chain of the OSM receptor and inhibits IL-31 and OSM signalling. Vixarelimab can be used in studies of inflammatory skin diseases such as atopic dermatitis and itchy nodular rash .

HY-B1616R

Clobetasone butyrate (Standard)	Glucocorticoid Receptor	Inflammation/Immunology
Clobetasone butyrate (Standard) is the analytical standard of Clobetasone butyrate. This product is intended for research and analytical applications. Clobetasone butyrate is a synthetic glucocorticoid and has topical anti-inflammatory activity especially in skin. Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis and psoriasis .

HY-106996

AWD 12-281 GW 842470	Phosphodiesterase (PDE)	Inflammation/Immunology
AWD 12-281 is an orally active and highly selective phosphodiesterase 4 (PDE4) inhibitor (IC₅₀ = 9.7 nM). AWD 12-281 is used in the study of allergic dermatitis, asthma, chronic obstructive pulmonary disease (COPD), and allergic rhinitis .

HY-13723A

Pimecrolimus hydrate SDZ-ASM 981 hydrate	Phosphatase	Inflammation/Immunology
Pimecrolimus hydrate (SDZ-ASM 981 hydrate) is a potent, nonsteroid and orally active calcineurin inhibitor. Pimecrolimus hydrate shows anti-inflammatory activity. Pimecrolimus hydrate has the potential for the research of atopic dermatitis and oral erosive lichen planus .

HY-106714

Clocortolone pivalate	Drug Metabolite	Inflammation/Immunology
Clocortolone pivalate is a synthetic glucocorticoid corticosteroid and corticosteroid ester. Clocortolone pivalate is indicated for seborrheic dermatitis, contact dermatitis, atopic dermatitis and psoriasis .

HY-B0688

Dapsone 1 Publications Verification 4,4′-Diaminodiphenyl sulfone; DDS	Antibiotic Parasite Bacterial Reactive Oxygen Species	Infection Inflammation/Immunology
Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-A0255

Clocortolone	Drug Metabolite	Inflammation/Immunology
Clocortolone is a synthetic glucocorticoid steroid and corticosteroid ester. Clocortolone can be used for seborrheic dermatitis, contact dermatitis, atopic dermatitis, and psoriasis. Clocortolone has local in vivo potency and is not easily absorbed into systemic circulation .

HY-B0688R

Dapsone (Standard)	Antibiotic Parasite Bacterial Reactive Oxygen Species	Infection Inflammation/Immunology
Dapsone (Standard) is the analytical standard of Dapsone. This product is intended for research and analytical applications. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-106714R

Clocortolone pivalate (Standard)	Drug Metabolite	Inflammation/Immunology
Clocortolone pivalate (Standard) is the analytical standard of Clocortolone pivalate. This product is intended for research and analytical applications. Clocortolone pivalate is a synthetic glucocorticoid corticosteroid and corticosteroid ester. Clocortolone pivalate is indicated for seborrheic dermatitis, contact dermatitis, atopic dermatitis and psoriasis .

HY-B0328

Triamcinolone 2 Publications Verification	Glucocorticoid Receptor Interleukin Related	Inflammation/Immunology Endocrinology Cancer
Triamcinolone is a long-acting corticosteroid with anti-inflammatory, anti-oedematous, anti-proliferative, anti-angiogenetic, immunomodulatory and neuroprotective effects through binding to glucocorticoid receptors. Triamcinolone can relieve several dermatitis, immune diseases and ocular diseases .

HY-B1387

Sulfamethoxypyridazine	PD-1/PD-L1 Bacterial Antibiotic	Infection
Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic, for treatment of Dermatitis herpetiformis.

HY-160761

K-Opioid receptor agonist-1	Opioid Receptor	Inflammation/Immunology
K-Opioid receptor agonist-1 (Compound 5a) is an agonist for κ-Opioid receptor with K_i of 0.25 nM and EC₅₀ of 2 nM. K-Opioid receptor agonist-1 is blood brain barrier (BBB) penetrate (brain/plasma ratios of 0.50 to 0.65). K-Opioid receptor agonist-1 exhibits anti-inflammatory activity in dermatitis models induced by Arachidonic acid (HY-109590) or oxazolidinone .

HY-14939

Vapitadine	Others	Inflammation/Immunology
Vapitadine is a non-sedative antihistamine compound that alleviates itching associated with atopic dermatitis.

HY-163498

NLRP3-IN-37	NOD-like Receptor (NLR)	Neurological Disease Inflammation/Immunology
NLRP3-IN-37 (Compound 23) is a NLRP3 inhibitor (EC₅₀: 5 nM). NLRP3-IN-37 can be used for NLRP3 related research, such as gout, pseudogout, CAPS, NASH fibrosis, heart failure, idiophathic pericarditis, atopic dermatitis, inflammatory bowel disease, Alzheimer's Disease, Parkinson's Disease and traumatic brain injury .

HY-145351

BAY 1003803	Glucocorticoid Receptor	Inflammation/Immunology
BAY 1003803 is a glucocorticoid receptor agonist for the topical research of psoriasis or severe atopic dermatitis.

HY-P99025

Lebrikizumab TNX-650	Interleukin Related	Neurological Disease Inflammation/Immunology
Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases .

HY-18706

trans-Tranilast trans-MK-341; trans-SB 252218	Angiotensin Receptor	Inflammation/Immunology Endocrinology
trans-Tranilast (trans-MK-341) is an antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.

HY-106566

Alclometasone dipropionate Sch 22219	Others	Inflammation/Immunology
Alclometasone dipropionate (Sch 22219) is a steroid compound. Alclometasone dipropionate can be used for the research of dermatitis and skin itch .

HY-121456

Salnacedin G-201	Others	Inflammation/Immunology
Salnacedin (G-201) has anti-inflammatory and keratolytic activity. Salnacedin can be used in the research of seborrhoeic dermatitis and acne .

HY-N0184A

Dipotassium glycyrrhizinate 20+ Cited Publications Glycyrrhizic acid dipotassium; Dipotassium glycyrrhizate	Virus Protease	Metabolic Disease Inflammation/Immunology
Dipotassium glycyrrhizinate is a HMGB1 inhibitor, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity .

HY-P99018

Etokimab Antibody ANB 020	Interleukin Related	Cancer
Etokimab (Antibody ANB 020) is a humanized monoclonal antibody that targets IL-33. Etokimab can be used for the research of atopic dermatitis .

HY-156621

Lepzacitinib	JAK	Inflammation/Immunology
Lepzacitinib is a Janus kinase inhibitor targeting to JAK 1/3. Lepzacitinib exhibits anti-inflammatory effect and inhibits atopic dermatitis and other skin diseases .

HY-130313

Sodium lauroyl glutamate	Amino Acid Derivatives	Inflammation/Immunology
Sodium lauroyl glutamate is an anionic amino acid surfactant. Sodium lauroyl glutamate has the irritant contact dermatitis potential, and possible anti-irritating potential in a surfactant mixture on human skin .

HY-B0894

Resorcinol monoacetate Acetylresorcinol; Resorcin monoacetate	Biochemical Assay Reagents	Inflammation/Immunology
Resorcinol monoacetate (Acetylresorcinol) is an antiseptic and a disinfectant, is a chemical intermediate for the production of many other pharmaceuticals, and has the potential for acne, seborrheic dermatitis, eczema, psoriasis, and other skin disorders research.

Cat. No.	Product Name	Type

HY-66019

FITC

40+ Cited Publications

Fluorescein 5-isothiocyanate

Fluorescent Dyes/Probes

FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .

Cat. No.	Product Name	Type

HY-156263

LB Broth Base, powder Luria-Bertani Base	Microbial Culture
LB Broth Base, powder (Luria-Bertani Base) is generally used to maintain the growth of E. coli. The composition of 1 liter of LB medium is: 10 g peptone, 5 g yeast extract and 5 g NaCl .

Cat. No.	Product Name	Target	Research Area

HY-P1722

Spantide II	Neurokinin Receptor	Inflammation/Immunology
Spantide II, an undecapeptide substance P (SP) analog, is a potent neurokinin-1 receptor (NK-1R) antagonist. Spantide II binds with NK-1R and blocks proinflammatory activities associated with SP. Spantide II can be used in the research of inflammatory skin disorders, such as psoriasis and contact dermatitis .

HY-P10415

EPI-X4 hSA(408–423) peptide	CXCR	Infection Inflammation/Immunology Cancer
EPI-X4 (hSA408–423 peptide) is an antagonist for C-X-C motif chemokine receptor 4 (CXCR4) with IC₅₀ of 8.6 μM. EPI-X4 blocks the CXCL12-mediated signaling, inhibits chemokine-mediated migration and invasion of leukemia cell. EPI-X4 exhibits anti-inflammatory activity in mouse model. EPI-X4 exhibits antiviral activity against CXCR4-tropic HIV with IC₅₀ of 8.6 μM .

Cat. No.	Product Name	Target	Research Area

HY-P99301

Lokivetmab Anti-Canine IL31 Recombinant Antibody	Interleukin Related	Inflammation/Immunology
Lokivetmab (Anti-Canine IL31 Recombinant Antibody) is an anti-canine IL-31 monoclonal antibody that can be used for the research of atopic dermatitis (AD) in dogs .

HY-P99053

Tralokinumab	Interleukin Related	Inflammation/Immunology
Tralokinumab, a fully human IgG4 monoclonal antibody, specifically binds with high affinity to IL-13 alone, preventing its interaction with the receptor and subsequent downstream signalling. Tralokinumab can be used for the research of the atopic dermatitis (AD) .

HY-P99434

Amlitelimab KY1005; SAR445229	Inhibitory Antibodies	Inflammation/Immunology
Amlitelimab () is an anti-OX40 Ligand (OX40L) monoclonal antibody (mAb). Amlitelimab inhibits OX40-OX40L interaction, and can be used in the research of atopic dermatitis .

HY-P99162

Nemolizumab CIM331	Interleukin Related	Inflammation/Immunology
Nemolizumab (CIM331) is a humanized monoclonal antibody that targets the human interleukin-31 receptor a, preventing interleukin-31 (IL-31) from binding to its receptor and the subsequent signaling. Nemolizumab can help reduce itching and sleep disturbances, and it is being studied for atopic dermatitis (AD) .

HY-P99955

Rocatinlimab AMG 451; KHK4083	Inhibitory Antibodies	Infection Inflammation/Immunology
Rocatinlimab (AMG 451) (KHK4083) is a fully human, non-fucosylated, immunoglobulin G1 (IgG1) anti-OX40 monoclonal antibody. Rocatinlimab can be used for the research of atopic dermatitis (AD) .

HY-P99519

Vixarelimab 1 Publications Verification KPL-716	Interleukin Related	Inflammation/Immunology
Vixarelimab (KPL-716) is a human anti-oncostatin M (OSM) monoclonal antibody that binds to the beta chain of the OSM receptor and inhibits IL-31 and OSM signalling. Vixarelimab can be used in studies of inflammatory skin diseases such as atopic dermatitis and itchy nodular rash .

HY-P99025

Lebrikizumab TNX-650	Interleukin Related	Neurological Disease Inflammation/Immunology
Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases .

HY-P99018

Etokimab Antibody ANB 020	Interleukin Related	Cancer
Etokimab (Antibody ANB 020) is a humanized monoclonal antibody that targets IL-33. Etokimab can be used for the research of atopic dermatitis .

HY-P9926

Dupilumab 1 Publications Verification REGN-668; SAR-231893	Interleukin Related	Inflammation/Immunology Cancer
Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis .

HY-P99673

Itepekimab REGN-3500; SAR-440340	Interleukin Related NF-κB	Inflammation/Immunology
Itepekimab (REGN-3500) is an IgG4 monoclonal antibody against IL-33. Itepekimab reduced airway inflammation and related tissue damage in preliminary clinical studies. Itepekimab has potential effects in asthma, chronic obstructive pulmonary disease (COPD), and atopic dermatitis (AD) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0508

Rosin 1 Publications Verification	Structural Classification Classification of Application Fields Simple Phenylpropanols Rhodiola rosea Linn. Crassulaceae Source classification Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Others
Rosin is isolated from pine wood or pine stumps, Rosin is a frequent contact allergen which induces allergic contact dermatitis .

HY-B0328

Triamcinolone 2 Publications Verification	Classification of Application Fields Source classification Solanum lyratum Thunberg Solanaceae Plants Inflammation/Immunology Disease Research Fields Steroids Cancer	Glucocorticoid Receptor Interleukin Related
Triamcinolone is a long-acting corticosteroid with anti-inflammatory, anti-oedematous, anti-proliferative, anti-angiogenetic, immunomodulatory and neuroprotective effects through binding to glucocorticoid receptors. Triamcinolone can relieve several dermatitis, immune diseases and ocular diseases .

HY-N0184A

Dipotassium glycyrrhizinate Maximum Cited Publications 25 Publications Verification Glycyrrhizic acid dipotassium; Dipotassium glycyrrhizate	Triterpenes Structural Classification Classification of Application Fields Leguminosae Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields Glycyrrhiza uralensis Fisch.	Virus Protease
Dipotassium glycyrrhizinate is a HMGB1 inhibitor, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity .

HY-N3312

Matairesinol	Infection Structural Classification other families Classification of Application Fields Anti-aging Source classification Lignans Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields	Endogenous Metabolite
Matairesinol confers anti-allergic effects in an allergic dermatitis mouse model. DfE-induced changes in IL-4 and IFN-γ mRNA expression in the ears of NC/Nga mice were reversed by matairesinol application .

HY-P9926

Dupilumab 1 Publications Verification REGN-668; SAR-231893	Classification of Application Fields Disease Research Fields Cancer	Interleukin Related
Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis .

HY-13516

Aloperine 4 Publications Verification	Infection Alkaloids Piperidine Alkaloids Structural Classification Classification of Application Fields Leguminosae Source classification Sophora alopecuroides L Plants Inflammation/Immunology Disease Research Fields	Apoptosis Autophagy Filovirus HIV
Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties . Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China . Aloperine induces apoptosis and autophagy in HL-60 cells .

HY-N4042

Hirsutenone	Structural Classification Classification of Application Fields Alnus cremastogyne Burk. Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Betulaceae	PI3K ERK
Hirsutenone is an active botanical diarylheptanoid present in Alnus species and exhibits many biological activities, including anti-inflammatory, anti-tumor promoting and anti-atopic dermatitis effects. Hirsutenone attenuates adipogenesis by binding directly to PI3K and ERK1 in a non-ATP competitive manner. Hirsutenone can be used for the study of obesity .

HY-159514

Graveolide	Structural Classification Terpenoids Sesquiterpenes Source classification Plants Compositae Erythrina arborescens Roxb.	NO Synthase COX
Graveolide (Compound 5) is a sesquiterpenoid compound that can be isolated from C. abrotanoides. Graveolide possesses anti-inflammatory activity and can be utilized in the research of atopic dermatitis .

HY-N0508R

Rosin (Standard)	Structural Classification Simple Phenylpropanols Rhodiola rosea Linn. Crassulaceae Source classification Phenylpropanoids Plants	Others
Rosin (Standard) is the analytical standard of Rosin. This product is intended for research and analytical applications. Rosin is isolated from pine wood or pine stumps, Rosin is a frequent contact allergen which induces allergic contact dermatitis .

HY-N3312R

Matairesinol (Standard)	Structural Classification other families Source classification Lignans Phenols Polyphenols Phenylpropanoids Plants	Endogenous Metabolite
Matairesinol (Standard) is the analytical standard of Matairesinol. This product is intended for research and analytical applications. Matairesinol confers anti-allergic effects in an allergic dermatitis mouse model. DfE-induced changes in IL-4 and IFN-γ mRNA expression in the ears of NC/Nga mice were reversed by matairesinol application .

Cat. No.	Product Name	Chemical Structure

HY-B0688S1

Dapsone-d4

Dapsone-d₄ is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities[1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al[2][3].

HY-B0688S2

Dapsone-13C12

Dapsone- ¹³C₁₂ is the ¹³C₁₂ labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

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