1. Inhibitory Antibodies
  2. Amlitelimab

Amlitelimab  (Synonyms: KY1005; SAR445229)

Cat. No.: HY-P99434 Purity: 98.00%
COA

Alvircept sudotox is an anti-OX40 Ligand (OX40L) monoclonal antibody (mAb). Alvircept sudotox inhibits OX40-OX40L interaction, and can be used in the research of atopic dermatitis.

For research use only. We do not sell to patients.

Size Price Stock Quantity
1 mg USD 300 In-stock
5 mg USD 780 In-stock
10 mg USD 1250 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

Alvircept sudotox is an anti-OX40 Ligand (OX40L) monoclonal antibody (mAb). Alvircept sudotox inhibits OX40-OX40L interaction, and can be used in the research of atopic dermatitis[1][2][3].

Isotype

Human IgG4 kappa

Recommend Isotype Controls
In Vitro

Amlitelimab (150 μg/mL) inhibits proliferation of human CD3 T cells[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Amlitelimab]

Shipping

Shipping with dry ice.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG4 kappa
Biological Activity
  • Loaded Amlitelimab on AHC2 biosensor, can bind OX40 Ligand/TNFSF4 (HEK293, His, HY-P70622) with an affinity constant of <1.000E-11 M as determined in BLI assay.
Purity & Documentation

Purity: 98.23%

References
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Amlitelimab Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Amlitelimab
Cat. No.:
HY-P99434
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