2. Immunology/Inflammation Vitamin D Related/Nuclear Receptor
  3. Glucocorticoid Receptor
  4. Prednicarbate

Prednicarbate is a topical corticosteroid agent. Prednicarbate can be used for the research of inflammatory skin diseases, such as atopic dermatitis.

For research use only. We do not sell to patients.

Prednicarbate Chemical Structure

Prednicarbate Chemical Structure

CAS No. : 73771-04-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Prednicarbate:

Prednicarbate Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Prednicarbate is a topical corticosteroid agent. Prednicarbate can be used for the research of inflammatory skin diseases, such as atopic dermatitis[1][2].

In Vitro

Prednicarbate (0.25%; applied daily to the ear skin area for 2 days) recovers the 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis of mice[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Prednicarbate Related Antibodies
Clinical Trial
Molecular Weight

488.57

Formula

C27H36O8
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCC(OCC([C@@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@@]4(C(CC3)=CC(C=C4)=O)C)([H])[C@H](C2)O)([H])CC1)C)OC(OCC)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 33.33 mg/mL (68.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0468 mL 10.2339 mL 20.4679 mL
5 mM 0.4094 mL 2.0468 mL 4.0936 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0468 mL 10.2339 mL 20.4679 mL 51.1697 mL
5 mM 0.4094 mL 2.0468 mL 4.0936 mL 10.2339 mL
10 mM 0.2047 mL 1.0234 mL 2.0468 mL 5.1170 mL
15 mM 0.1365 mL 0.6823 mL 1.3645 mL 3.4113 mL
20 mM 0.1023 mL 0.5117 mL 1.0234 mL 2.5585 mL
25 mM 0.0819 mL 0.4094 mL 0.8187 mL 2.0468 mL
30 mM 0.0682 mL 0.3411 mL 0.6823 mL 1.7057 mL
40 mM 0.0512 mL 0.2558 mL 0.5117 mL 1.2792 mL
50 mM 0.0409 mL 0.2047 mL 0.4094 mL 1.0234 mL
60 mM 0.0341 mL 0.1706 mL 0.3411 mL 0.8528 mL
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Prednicarbate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Prednicarbate73771-04-7Glucocorticoid Receptorcorticosteroidinflammatoryskin diseasesatopic dermatitisInhibitorinhibitorinhibit

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